NaPi 2c

General Information (Source: NCBI Gene,UniProt)

Text mining Term NaPi 2c
UniProt ID NPT2C_RAT
Name NaPi-2c
Na(+)-dependent phosphate cotransporter 2C
Solute carrier family 34 member 3
Na(+)/Pi cotransporter 2C
Sodium-phosphate transport protein 2C
Sodium-dependent phosphate transport protein 2C
Sodium/phosphate cotransporter 2C
Gene Names Slc34a3
Taxonomy Rattus norvegicus

General annotation

Function May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane. Probably mediates 20-30% of the apical influx.
Subcellular location Membrane; Multi-pass membrane protein.

Gene Ontology

GO:0032026 response to magnesium ion BP
GO:0005436 sodium MF
GO:0015321 sodium-dependent phosphate transmembrane transporter activity MF
GO:0031526 brush border membrane CC
GO:0031667 response to nutrient levels BP
GO:0016021 integral to membrane CC
GO:0031410 cytoplasmic vesicle CC
GO:0016324 apical plasma membrane CC

Sequence

>gi|21326473|ref|NP_647554.1| sodium-dependent phosphate transport protein 2C [Rattus norvegicus]
MPNSLAGDQVPNPTLDAIGLVDWSLRNAGTSGSTPGLEEGGTDPWTFSQLKNTDQLKEVGTASKLHQVVS
GFLKACGLLGSLYFFICSLDILSSAFQLLGSKMAGDIFKDNVVLSNPVAGLVIGVVVTVLVQSSSTSSSI
VVSMVASKSLTVQASVPIIMGVNVGTSITSTLVSMAQSGDRDEFQRAFGGSAVHGIFNWLTVLVLLPLEN
ATAALERLSELALGAASLQPGGQAPDILKALTRPFTHLIIQLDSSVVTSSITSNTTNSSLIKHWCGFRGE
TPQGSSEECDLSGSCTERNSSASPGEDRLLCHHLFAGSELTDLAVGFILLAGSLLVLCVCLVLIVKLLNS
VLRGRIAQAVKTVINADFPFPFGWLSGYLAILVGAGLTFLLQSSSVFTAAIVPLMGVGVINLERAYPLFL
GSNIGTTTTALLAALASPADTLLFAVQVALIHFFFNLAGILLWYLVPVLRLPIPLAKRFGDLTAQYRWVA
IVYLLLTFLLLPLAAFGLSLAGGSVLAAVGGPLVGLVLLIILVNVLQRHRPSWLPRRLQSWAWLPLWLHS
LEPWDRLVTGCCPFKAYSNSHMTSKVAHCYENPQVIASQQL

Options for BLAST

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Database Cross Reference

Ensembl Gene
UniGene Rn.15318
PDB
RefSeq NP_647554.1
Pfam PF02690