matrix Gla protein

General Information (Source: NCBI Gene,UniProt)

Text mining Term matrix Gla protein
UniProt ID MGP_RAT
Name Matrix Gla protein
MGP
Gene Names Mgp
Taxonomy Rattus norvegicus

General annotation

Function Associates with the organic matrix of bone and cartilage. Thought to act as an inhibitor of bone formation.
Subcellular location Secreted.

Gene Ontology

GO:0048754 branching morphogenesis of a tube BP
GO:0030154 cell differentiation BP
GO:0009612 response to mechanical stimulus BP
GO:0005509 calcium ion binding MF
GO:0005783 endoplasmic reticulum CC
GO:0043234 protein complex CC
GO:0030324 lung development BP
GO:0007584 response to nutrient BP
GO:0051592 response to calcium ion BP
GO:0001503 ossification BP
GO:0005615 extracellular space CC
GO:0031012 extracellular matrix CC
GO:0030500 regulation of bone mineralization BP
GO:0009725 response to hormone stimulus BP
GO:0048306 calcium-dependent protein binding MF
GO:0051216 cartilage development BP

Sequence

>gi|6981204|ref|NP_036994.1| matrix Gla protein precursor [Rattus norvegicus]
MKSLLPLAILAALAVAALCYESHESMESYEVSPFTTRRNANTFISPQQRWHAKAQERVRELNKPAQEINR
EACDDYKLCERYALIYGYNAAYNRYFRQRRGAK

Options for BLAST

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Database Cross Reference

Ensembl Gene
UniGene Rn.2379
PDB
RefSeq NP_036994.1
Pfam PF00594