alpha fetoprotein

General Information (Source: NCBI Gene,UniProt)

Text mining Term alpha fetoprotein
UniProt ID FETA_MOUSE
Name Alpha-fetoprotein
Alpha-fetoglobulin
Alpha-1-fetoprotein
Gene Names Afp
Taxonomy Mus musculus

General annotation

Function Binds estrogens, fatty acids and metals.
Subcellular location Secreted.

Gene Ontology

GO:0006810 transport BP
GO:0060395 SMAD protein signal transduction BP
GO:0005615 extracellular space CC
GO:0042448 progesterone metabolic process BP
GO:0046872 metal ion binding MF
GO:0005737 cytoplasm CC
GO:0001542 ovulation from ovarian follicle BP

Sequence

>gi|163310738|ref|NP_031449.3| alpha-fetoprotein precursor [Mus musculus]
MKWITPASLILLLHFAASKALHENEFGIASTLDSSQCVTEKNVLSIATITFTQFVPEATEEEVNKMTSDV
LAAMKKNSGDGCLESQLSVFLDEICHETELSNKYGLSGCCSQSGVERHQCLLARKKTAPASVPPFQFPEP
AESCKAHEENRAVFMNRFIYEVSRRNPFMYAPAILSLAAQYDKVVLACCKADNKEECFQTKRASIAKELR
EGSMLNEHVCSVIRKFGSRNLQATTIIKLSQKLTEANFTEIQKLALDVAHIHEECCQGNSLECLQDGEKV
MTYICSQQNILSSKIAECCKLPMIQLGFCIIHAENGVKPEGLSLNPSQFLGDRNFAQFSSEEKIMFMASF
LHEYSRTHPNLPVSVILRIAKTYQEILEKCSQSGNLPGCQDNLEEELQKHIEESQALSKQSCALYQTLGD
YKLQNLFLIGYTRKAPQLTSAELIDLTGKMVSIASTCCQLSEEKWSGCGEGMADIFIGHLCIRNEASPVN
SGISHCCNSSYSNRRLCITSFLRDETYAPPPFSEDKFIFHKDLCQAQGKALQTMKQELLINLVKQKPELT
EEQLAAVTADFSGLLEKCCKAQDQEVCFTEEGPKLISKTRDALGV

Options for BLAST

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Database Cross Reference

Ensembl Gene ENSMUST00000042755
UniGene Mm.358570
PDB
RefSeq NP_031449.3
Pfam PF00273