Keratinocyte growth factor

General Information (Source: NCBI Gene,UniProt)

Text mining Term Keratinocyte growth factor
UniProt ID FGF7_RAT
Name KGF
HBGF-7
Heparin-binding growth factor 7
FGF-7
Fibroblast growth factor 7
Keratinocyte growth factor
Gene Names Fgf7
Taxonomy Rattus norvegicus

General annotation

Function Growth factor active on keratinocytes. Possible major paracrine effector of normal epithelial cell proliferation.
Subcellular location

Gene Ontology

GO:0006656 phosphatidylcholine biosynthetic process BP
GO:0005615 extracellular space CC
GO:0001541 ovarian follicle development BP
GO:0051781 positive regulation of cell division BP
GO:0008201 heparin binding MF
GO:0042060 wound healing BP
GO:0005111 type 2 fibroblast growth factor receptor binding MF
GO:0043129 surfactant homeostasis BP
GO:0008083 growth factor activity MF

Sequence

>gi|11559943|ref|NP_071518.1| keratinocyte growth factor precursor [Rattus norvegicus]
MRKWILTRILPTPLYRPCFHLVCLVGTISLACNDMSPEQTATSVNCSSPERHTRSYDYMEGGDIRVRRLF
CRTQWYLRIDKRGKVKGTQEMRNSYNIMEIMTVAVGIVAIKGVESEYYLAMNKQGELYAKKECNEDCNFK
ELILENHYNTSASAKWTHSGGEMFVALNQKGLPVKGKKTKKEQKTAHFLPMAIT

Options for BLAST

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Database Cross Reference

Ensembl Gene
UniGene Rn.98842
PDB 1QQK
1QQL
RefSeq NP_071518.1
Pfam PF00167