semicarbazide sensitive amine oxidase

General Information (Source: NCBI Gene,UniProt)

Text mining Term semicarbazide sensitive amine oxidase
UniProt ID AOC3_MOUSE
Name Vascular adhesion protein 1
SSAO
VAP-1
Semicarbazide-sensitive amine oxidase
Membrane primary amine oxidase
Copper amine oxidase
Gene Names Aoc3
Synonyms:Vap1
Taxonomy Mus musculus

General annotation

Function Cell adhesion protein that participates in lymphocyte recirculation by mediating the binding of lymphocytes to peripheral lymph node vascular endothelial cells in an L-selectin- independent fashion. Has a monoamine oxidase activity. May play a role in adipogenesis (By similarity).
Subcellular location Membrane; Single-pass type II membrane protein (By similarity).

Gene Ontology

GO:0005507 copper ion binding MF
GO:0052593 tryptamine MF
GO:0009308 amine metabolic process BP
GO:0008131 primary amine oxidase activity MF
GO:0007155 cell adhesion BP
GO:0052596 phenethylamine MF
GO:0048038 quinone binding MF
GO:0016021 integral to membrane CC
GO:0052594 aminoacetone MF
GO:0052595 aliphatic-amine oxidase activity MF
GO:0005886 plasma membrane CC
GO:0009986 cell surface CC

Sequence

>gi|6753066|ref|NP_033805.1| membrane primary amine oxidase [Mus musculus]
MTQKTTLVLLALAVITIFALVCVLLAGRSGDGGGLSQPLHCPSVLPSVQPRTHPSQSQPFADLSPEELTA
VMSFLTKHLGPGLVDAAQARPSDNCVFSVELQLPAKAAALAHLDRGGPPPVREALAIIFFGGQPKPNVSE
LVVGPLPHPSYMRDVTVERHGGPLPYYRRPVLDREYQDIEEMIFHRELPQASGLLHHCCFYKHQGQNLLT
MTTAPRGLQSGDRATWFGLYYNLSGAGFYPHPIGLELLIDHKALDPALWTIQKVFYQGRYYESLTQLEDQ
FEAGLVNVVLVPNNGTGGSWSLKSSVPPGPAPPLQFHPQGPRFSVQGSQVSSSLWAFSFGLGAFSGPRIF
DIRFQGERVAYEISVQEAIALYGGNSPASMSTCYVDGSFGIGKYSTPLIRGVDCPYLATYVDWHFLLESQ
APKTLRDAFCVFEQNQGLPLRRHHSDFYSHYFGGVVGTVLVVRSVSTLLNYDYIWDMVFHPNGAIEVKFH
ATGYISSAFFFGAGEKFGNRVGAHTLGTVHTHSAHFKVDLDVAGLKNWAWAEDMAFVPTIVPWQPEYQMQ
RLQVTRKLLETEEEAAFPLGGATPRYLYLASNHSNKWGHRRGYRIQILSFAGKPLPQESPIEKAFTWGRY
HLAVTQRKEEEPSSSSIFNQNDPWTPTVNFTDFISNETIAGEDLVAWVTAGFLHIPHAEDIPNTVTAGNS
VGFFLRPYNFFDEDPSFHSADSIYFREGQDATACEVNPLACLSQTATCAPEIPAFSHGGFAYRDN

Options for BLAST

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Database Cross Reference

Ensembl Gene ENSMUST00000103105
UniGene Mm.67281
PDB
RefSeq NP_033805.1
Pfam PF02728
PF01179
PF02727