| Text mining Term | Nociceptin |
|---|---|
| UniProt ID | PNOC_MOUSE |
| Name |
Orphanin FQ Neuropeptide 2 Prepronociceptin N23K/N27K Neuropeptide 1 PPNOC Nociceptin |
| Gene Names |
Pnoc
Synonyms:Npnc1 |
| Taxonomy | Mus musculus |
| Function |
Nociceptin is the ligand of the opioid receptor-like receptor (OPRL1). It may act as a transmitter in the brain by modulating nociceptive and locomotor behavior. May be involved in neuronal differentiation and development. When administered intracerebroventricularly, nociceptin induces hyperalgesia and decreases locomotor activity. |
|---|---|
| Subcellular location |
Secreted. |
| GO:0007268 | synaptic transmission | BP |
| GO:0007218 | neuropeptide signaling pathway | BP |
| GO:0005576 | extracellular region | CC |
| GO:0001515 | opioid peptide activity | MF |
>gi|326537301|ref|NP_001192004.1| prepronociceptin isoform 2 preproprotein [Mus musculus] MKILFCDVLLLSLLSSVFSSCPRDCLTCQEKLHPAPDSFNLKTCILQCEEKVFPRPLWTVCTKVMASGSG QLSPADPELVSAALYQPKASEMQHLKRMPRVRSLVQVRDAEPGADAEPGADAEPGADDAEEVEQKQLQKR FGGFTGARKSARKLANQKRFSEFMRQYLVLSMQSSQRRRTLHQNGIQVIPRTACVHSKTCRPGVRIPPSP RH |
| Ensembl Gene |
ENSMUST00000059339 |
|---|---|
| UniGene |
Mm.16347 |
| PDB | |
| RefSeq |
NP_035062.1 NP_001192004.1 |
| Pfam |
PF01160 |