Glucose dependent insulinotropic polypeptide

General Information (Source: NCBI Gene,UniProt)

Text mining Term Glucose dependent insulinotropic polypeptide
UniProt ID GIP_RAT
Name GIP
Glucose-dependent insulinotropic polypeptide
Gastric inhibitory polypeptide
Gene Names Gip
Taxonomy Rattus norvegicus

General annotation

Function Potent stimulator of insulin secretion and relatively poor inhibitor of gastric acid secretion.
Subcellular location Secreted.

Gene Ontology

GO:0042594 response to starvation BP
GO:0043950 positive regulation of cAMP-mediated signaling BP
GO:0070094 positive regulation of glucagon secretion BP
GO:0010269 response to selenium ion BP
GO:0043025 neuronal cell body CC
GO:0048678 response to axon injury BP
GO:0005179 hormone activity MF
GO:0043200 response to amino acid stimulus BP
GO:0070328 triglyceride homeostasis BP
GO:0060291 long-term synaptic potentiation BP
GO:0014070 response to organic cyclic compound BP
GO:0005737 cytoplasm CC
GO:0032024 positive regulation of insulin secretion BP
GO:0043434 response to peptide hormone stimulus BP
GO:0010828 positive regulation of glucose transport BP
GO:0005576 extracellular region CC
GO:0042493 response to drug BP
GO:0007565 female pregnancy BP
GO:0009749 response to glucose stimulus BP
GO:0055123 digestive system development BP

Sequence

>gi|9789965|ref|NP_062604.1| gastric inhibitory polypeptide precursor [Rattus norvegicus]
MVALKTCSLLLVLLFLAVGLGEKEEVEFRSHAKFAGPRPRGPRYAEGTFISDYSIAMDKIRQQDFVNWLL
AQKGKKNDWKHNLTQREARALELAGQSQRNEEKEAQGSSLPKSLSDEDVLRDLLIQELLAWMADQAELCR
LRSQ

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Database Cross Reference

Ensembl Gene ENSRNOT00000008481
UniGene Rn.10446
PDB
RefSeq NP_062604.1
Pfam PF00123