galanin

General Information (Source: NCBI Gene,UniProt)

Text mining Term galanin
UniProt ID GALA_RAT
Name GMAP
Galanin
Galanin message-associated peptide
Galanin peptides
Gene Names Gal
Synonyms:Galn
Taxonomy Rattus norvegicus

General annotation

Function Contracts smooth muscle of the gastrointestinal and genitourinary tract, regulates growth hormone release, modulates insulin release, and may be involved in the control of adrenal secretion.
Subcellular location Secreted.

Gene Ontology

GO:0001664 G-protein coupled receptor binding MF
GO:0005794 Golgi apparatus CC
GO:0005179 hormone activity MF
GO:0032868 response to insulin stimulus BP
GO:0030141 secretory granule CC
GO:0031943 regulation of glucocorticoid metabolic process BP
GO:0007218 neuropeptide signaling pathway BP
GO:0042493 response to drug BP
GO:0050672 negative regulation of lymphocyte proliferation BP
GO:0006954 inflammatory response BP
GO:0005576 extracellular region CC
GO:0043065 positive regulation of apoptotic process BP
GO:0050776 regulation of immune response BP
GO:0043627 response to estrogen stimulus BP
GO:0007631 feeding behavior BP

Sequence

>gi|15147221|ref|NP_150240.1| galanin peptides preproprotein [Rattus norvegicus]
MARGSVILLAWLLLVATLSATLGLGMPTKEKRGWTLNSAGYLLGPHAIDNHRSFSDKHGLTGKRELPLEV
EEGRLGSVAVPLPESNIVRTIMEFLSFLHLKEAGALDSLPGIPLATSSEDLEQS

Options for BLAST

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Database Cross Reference

Ensembl Gene ENSRNOT00000020425
UniGene Rn.8929
PDB
RefSeq NP_150240.1
Pfam PF06540
PF01296