cytochrome P450 2E1

General Information (Source: NCBI Gene,UniProt)

Text mining Term cytochrome P450 2E1
UniProt ID CP2E1_MOUSE
Name Cytochrome P450-J
Cytochrome P450-ALC
Cytochrome P450 2E1
4-nitrophenol 2-hydroxylase
CYPIIE1
Gene Names Cyp2e1
Taxonomy Mus musculus

General annotation

Function Metabolizes several precarcinogens, drugs, and solvents to reactive metabolites (By similarity).
Subcellular location Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.

Gene Ontology

GO:0005792 microsome CC
GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen MF
GO:0009055 electron carrier activity MF
GO:0020037 heme binding MF

Sequence

>gi|11276065|ref|NP_067257.1| cytochrome P450 2E1 [Mus musculus]
MAVLGITVALLVWIATLLLVSIWKQIYRSWNLPPGPFPIPFFGNIFQLDLKDIPKSLTKLAKRFGPVFTL
HLGQRRIVVLHGYKAVKEVLLNHKNEFSGRGDIPVFQEYKNKGIIFNNGPTWKDVRRFSLSILRDWGMGK
QGNEARIQREAHFLVEELKKTKGQPFDPTFLIGCAPCNVIADILFNKRFDYDDKKCLELMSLFNENFYLL
STPWIQAYNYFSDYLQYLPGSHRKVMKNVSEIRQYTLGKAKEHLKSLDINCPRDVTDCLLIEMEKEKHSQ
EPMYTMENISVTLADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRAPAVRDRMNMPYM
DAVVHEIQRFINLVPSNLPHEATRDTVFRGYVIPKGTVVIPTLDSLLFDNYEFPDPETFKPEHFLNENGK
FKYSDYFKAFSAGKRVCVGEGLARMELFLLLSAILQHFNLKSLVDPKDIDLSPVTIGFGSIPREFKLCVI
PRS

Options for BLAST

Database:

Set subsequence:(optional):
From: To:

Optional parameters:
Expect:
Descriptions:

Database Cross Reference

Ensembl Gene ENSMUST00000026552
UniGene Mm.21758
PDB
RefSeq NP_067257.1
Pfam PF00067