P2X3

General Information (Source: NCBI Gene,UniProt)

Text mining Term P2X3
UniProt ID P2RX3_RAT
Name P2X3
Purinergic receptor
ATP receptor
P2X purinoceptor 3
Gene Names P2rx3
Taxonomy Rattus norvegicus

General annotation

Function Receptor for ATP that acts as a ligand-gated ion channel.
Subcellular location Membrane; Multi-pass membrane protein.

Gene Ontology

GO:0001614 purinergic nucleotide receptor activity MF
GO:0004931 extracellular ATP-gated cation channel activity MF
GO:0043025 neuronal cell body CC
GO:0005791 rough endoplasmic reticulum CC
GO:0005524 ATP binding MF
GO:0005794 Golgi apparatus CC
GO:0051260 protein homooligomerization BP
GO:0016021 integral to membrane CC
GO:0043195 terminal button CC
GO:0019717 synaptosome CC
GO:0043197 dendritic spine CC
GO:0045121 membrane raft CC
GO:0019228 regulation of action potential in neuron BP

Sequence

>gi|13592019|ref|NP_112337.1| P2X purinoceptor 3 [Rattus norvegicus]
MNCISDFFTYETTKSVVVKSWTIGIINRAVQLLIISYFVGWVFLHEKAYQVRDTAIESSVVTKVKGFGRY
ANRVMDVSDYVTPPQGTSVFVIITKIIVTENQMQGFCPENEEKYRCVSDSQCGPERFPGGGILTGRCVNY
SSVLRTCEIQGWCPTEVDTVEMPIMMEAENFTIFIKNSIRFPLFNFEKGNLLPNLTDKDIKRCRFHPEKA
PFCPILRVGDVVKFAGQDFAKLARTGGVLGIKIGWVCDLDKAWDQCIPKYSFTRLDGVSEKSSVSPGYNF
RFAKYYKMENGSEYRTLLKAFGIRFDVLVYGNAGKFNIIPTIISSVAAFTSVGVGTVLCDIILLNFLKGA
DHYKARKFEEVTETTLKGTASTNPVFASDQATVEKQSTDSGAYSIGH

Options for BLAST

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Database Cross Reference

Ensembl Gene
UniGene Rn.10388
PDB
RefSeq NP_112337.1
Pfam PF00864