alpha tubulin

General Information (Source: NCBI Gene,UniProt)

Text mining Term alpha tubulin
UniProt ID E1GGM8_LOALO
Name Alpha-tubulin
Gene Names
Taxonomy Loa loa

General annotation

Function Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain (By similarity).
Subcellular location

Gene Ontology

GO:0005874 microtubule CC
GO:0005198 structural molecule activity MF
GO:0005737 cytoplasm CC
GO:0003924 GTPase activity MF
GO:0005525 GTP binding MF
GO:0051258 protein polymerization BP
GO:0007018 microtubule-based movement BP

Sequence

>gi|312094041|ref|XP_003147889.1| alpha-tubulin [Loa loa]
MHTQTVIKLVTLKICLTCSHPFARLFNELQREVISLHVGQAGVQIGNACWELYCLEHGVQPDGMLPTDES
LGIEDSSYNTFFSETQAGKHVPRAIFIDLEPTVVDEVRTGTYKMLFHPEQLISGKEDAANNYARGHYTIG
KELIDVCMDRIRKLTERCDGLQGFLIFHSFGGGTGSGFTSLMMERLSVDYGKKAKLEFSIYPAPQISTAM
VEPYNSILTTHTTLEHSDCSFLVDNEAIYDICRKNLDIKRHFFLKLIPTYTNLNRLIAQIVSSITASLRF
DGALNVDLTEFQTNLVPYPRIHFPLATYSPIISAEKAFHEQLSVSEITNKCFEPGSQMVKCDPRNGKYMA
CCLLYRGDVVPKDVNSAIAMIKTKRAIHFVDWCPTGFKVGINYQPPTVVPGGDLAKLQRAVCMLSNTTAI
AEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGADSFDPVEDEY

Options for BLAST

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Database Cross Reference

Ensembl Gene
UniGene
PDB
RefSeq XP_003147889.1
Pfam PF03953
PF00091