PC 3

General Information (Source: NCBI Gene,UniProt)

Text mining Term PC 3
UniProt ID PSMD1_DROME
Name 26S proteasome regulatory subunit RPN2
26S proteasome non-ATPase regulatory subunit 1
26S proteasome regulatory complex subunit p110
Gene Names Rpn2
Taxonomy Drosophila melanogaster

General annotation

Function Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
Subcellular location

Gene Ontology

GO:0004175 endopeptidase activity MF
GO:0042176 regulation of protein catabolic process BP
GO:0005488 binding MF
GO:0030234 enzyme regulator activity MF
GO:0006974 response to DNA damage stimulus BP
GO:0006508 proteolysis BP
GO:0005838 proteasome regulatory particle CC

Sequence

>gi|51701864|sp|Q9V3P6.1|PSMD1_DROME RecName: Full=26S proteasome non-ATPase regulatory subunit 1; AltName: Full=26S proteasome regulatory complex subunit p110; AltName: Full=26S proteasome regulatory subunit RPN2
MSLTSAAGIISLLDEPMPDLKVFALKKLDNIVDEFWPEISESIEKIEMLHEDRSFPENKLAGMVASKVFY
HLGSFEDALTYALGAGDLFDVNARNEYTETIIAKCIDFYIAQRVEFIENPKEASVVDERLEGIVNRMIQR
CLDDNQFRQALGIALETRRMDTFKDAIMKSDDVRGMLAYAYNVTMSLIQNRGFRNEVLRCLVSLYRDLGV
PDYVNMCQCLIFLEDPFAVAEMLDNLTRSSVETNNLMAYQIAFDLYESATQEFLGNVLQHLKNTAPIPTA
LPSTFKPQGTTSEDGAKSEGDKSKSDEDITEETPADDKVERTIDSLNEVEKLHQKNIEKLISILSGEVSI
DLQLQFLIRSNHADLQVLRGTKEAVRVSICHTATVIANAFMHSGTTSDQFLRDNLDWLARATNWAKLTAT
ASLGVIHRGHEKDSLALMQSYLPKEAGPSSGYSEGGALYALGLIHANHGANIIDYLLQQLKDAQNENVRH
GGCLGLGLAGMGTHRQDLYEQLKFNLYQDDAVTGEAAGIAMGMVMLGSKNAQAIEDMVSYAQETQHEKIL
RGLAVGISLTMFSRLEEADPLVTSLSSDKDPVLRRSGMYTIAMAYNGTGSNKAIRKLLHVAVSDVNDDVR
RAAVTAIGFILFRSPEQCPSVVSLLAESYNPHVRYGAAMALGIACAGTGLREAIALLEPMVKFDPVNFVR
QGALIASAMILIQHTDQSCPKSTFFRQLYAEVISNKHEDVMAKYGAILAQGIIDAGGRNATLSLQSRTGH
TNLQAVVGMLAFTQYWYWFPLAHTLSLAFTPTCVIGLNSDLKMPKMEYKSAAKPSLYAYPAPLEEKKSEE
REKVATAVLSIAARQKRRENADKKEDEKMDVDEDSKEGAAVKKDEEAKADEKMVTDEKPKKKDEKEKKKE
EDKEKEAAGTSSEKDKDKEKDKKEKKEPEPTSEILQNPARVLRQQLKVLSVIDGQSYEPLKDVTIGGIIV
FQHTGKAEDQELVEPVAAFGPMNDEEKEPEPPEPFEYIED

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Database Cross Reference

Ensembl Gene
UniGene Dm.6875
PDB
RefSeq NP_651677.2
Pfam PF01851