| Text mining Term | NMDA receptor (protein family or complex) |
|---|---|
| UniProt ID | NMDA1_DROSI |
| Name |
Glutamate [NMDA] receptor subunit 1 |
| Gene Names |
Nmdar1
|
| Taxonomy | Drosophila simulans |
| Function |
NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. This protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors. Plays a role in associative learning and in long-term memory consolidation (By similarity). |
|---|---|
| Subcellular location |
Cell membrane; Multi-pass membrane protein (By similarity). Cell junction, synapse, postsynaptic cell membrane (By similarity). Cell junction, synapse, postsynaptic cell membrane, postsynaptic density (By similarity). |
| GO:0030288 | outer membrane-bounded periplasmic space | CC |
| GO:0007616 | long-term memory | BP |
| GO:0008355 | olfactory learning | BP |
| GO:0014069 | postsynaptic density | CC |
| GO:0042391 | regulation of membrane potential | BP |
| GO:0007268 | synaptic transmission | BP |
| GO:0030054 | cell junction | CC |
| GO:0045211 | postsynaptic membrane | CC |
| GO:0035235 | ionotropic glutamate receptor signaling pathway | BP |
| GO:0005234 | extracellular-glutamate-gated ion channel activity | MF |
| GO:0004970 | ionotropic glutamate receptor activity | MF |
| GO:0055074 | calcium ion homeostasis | BP |
| GO:0017146 | N-methyl-D-aspartate selective glutamate receptor complex | CC |
>gi|223635339|sp|B4QWW7.1|NMDA1_DROSI RecName: Full=Glutamate [NMDA] receptor subunit 1; Flags: Precursor MAVAGFVFCRPLFGLAIVLLVAPIDAAQRHTASDNPSTYNIGGVLSNSDSEEHFSTTIKHLNFDQQYVPR KVTYYDKTIRMDKNPIKTVFNVCDKLIENRVYAVVVSHEQTSGDLSPAAVSYTSGFYSIPVIGISSRDAA FSDKNIHVSFLRTVPPYYHQADVWLEMLSHFAYTKVIIIHSSDTDGRAILGRFQTTSQTYYDDVDVRATV ELIVEFEPKLESFTEHLIDMKTAQSRVYLMYASTEDAQVIFRDAGEYNMTGEGHVWIVTEQALFSNNTPD GVLGLQLEHAHSDKGHIRDSVYVLASAIKEMISNETIAEAPKDCGDSAVNWESGKRLFQYLKSRNITGET GQVAFDDNGDRIYAGYDVINIREQQKKHVVGKFSYDSMRAKMRMRINDSEIIWPGKQRRKPEGIMIPTHL KLLTIEEKPFVYVRRMGDDEFRCEPDERPCPLFNNSDATANEFCCRGYCIDLLIELSKRINFTYDLALSP DGQFGHYILRNSTGAMTLRKEWTGLIGELVNERADMIVAPLTINPERAEYIEFSKPFKYQGITILEKKPS RSSTLVSFLQPFSNTLWILVMVSVHVVALVLYLLDRFSPFGRFKLSHSDSNEEKALNLSSAVWFAWGVLL NSGIGEGTPRSFSARVLGMVWAGFAMIIVASYTANLAAFLVLERPKTKLSGINDARLRNTMENLTCATVK GSSVDMYFRRQVELSNMYRTMEANNYATAEQAIQDVKKGKLMAFIWDSSRLEYEASKDCELVTAGELFGR SGYGIGLQKGSPWTDAVTLAILEFHESGFMEKLDKQWIFHGHVQQNCELFEKTPNTLGLKNMAGVFILVG VGIAGGVGLIIIEVIYKKHQVKKQKRLDIARHAADKWRGTIEKRKTIRASLAMQRQYNVGLNSTHAPGTI SLAVDKRRYPRLGQRLGPERAWPGDAADVLRIRRPYELGKPGQSPKVMAANQPGMPMPMLGKTRPQQSVL PPRYSPGYTSDVSHLVV |
| Ensembl Gene | |
|---|---|
| UniGene | |
| PDB | |
| RefSeq |
XP_002102226.1 |
| Pfam |
PF10562 PF01094 PF00060 PF00497 |