sulfatase

General Information (Source: NCBI Gene,UniProt)

Text mining Term sulfatase
UniProt ID SULF1_DROME
Name Extracellular sulfatase SULF-1 homolog
DmSulf-1
Gene Names Sulf1
Taxonomy Drosophila melanogaster

General annotation

Function
Subcellular location Endoplasmic reticulum (By similarity). Golgi apparatus, Golgi stack (By similarity). Cell surface (By similarity). Note=Also localized on the cell surface (By similarity).

Gene Ontology

GO:0005783 endoplasmic reticulum CC
GO:0046872 metal ion binding MF
GO:0005795 Golgi stack CC
GO:0017015 regulation of transforming growth factor beta receptor signaling pathway BP
GO:0009986 cell surface CC
GO:0008484 sulfuric ester hydrolase activity MF
GO:0030111 regulation of Wnt receptor signaling pathway BP

Sequence

>gi|33112451|sp|Q9VEX0.1|SULF1_DROME RecName: Full=Extracellular sulfatase SULF-1 homolog; Short=DmSulf-1; Flags: Precursor
MMRHSSLRLIIGGLILLLFVLNVFSKEQGSHSHKRSHSAKRFSRDSNSARERRPNIILILTDDQDVELGS
LNFMPRTLRLLRDGGAEFRHAYTTTPMCCPARSSLLTGMYVHNHMVFTNNDNCSSPQWQATHETRSYATY
LSNAGYRTGYFGKYLNKYNGSYIPPGWREWGGLIMNSKYYNYSINLNGQKIKHGFDYAKDYYPDLIANDS
IAFLRSSKQQNQRKPVLLTMSFPAPHGPEDSAPQYSHLFFNVTTHHTPSYDHAPNPDKQWILRVTEPMQP
VHKRFTNLLMTKRLQTLQSVDVAVERVYNELKELGELDNTYIVYTSDHGYHLGQFGLIKGKSFPFEFDVR
VPFLIRGPGIQASKVVNEIVLNVDLAPTFLDMGGVPTPQHMDGRSILPLLLSRNRAVRDNWPDSFLIESS
GRRETAEQIAESRARLQIERRNMKLANSSLLEDFLEGAGESTTIVSSSSTAATLMSSTAQQPEDGEEEVE
TDNEEDDVDGDGAMDSSAAALEEDDLDDAAFEEGDEELDQEFQQNNDLPLAPYITKMMRLNSECSDPALL
KNCLPGQKWKCVNEEGRWRKHKCKFHLQLEHQLAAMPRKQYQRNCACFTPDGVVYTKIRAPSAGLHRVNK
RTHNGPGRRRNKREVFHTELPDEMEELLDLHQVVDQLVDHTHRSKRDLPASSNETIAQVIQQIQSTLEIL
ELKFNEHELHASNSSGNSYERGEKYTKSGGHRCFVDATTAKVNCSNVIYDDEKTWRTSRTQIDMLIKLLK
DKIGKLKEMKKQLRESNKQALAAGRRNDNRRRNDQSVLDSGAGPEFNMSYFTEISSTPRSNVVGQTEVFQ
GYGSASAFDSLEQTQSHRFTPRAECYCEPDVGENHADSKEMAREARRKLKEERQRKKERKRIKKARLEKE
CLSEKMNCFSHDNQHWRTAPLWNDSPFCFCMNANNNTYSCLRTINGTHNFLYCEFTTGLITFYNLTIDRF
ETINRAAGLTPGERSHMHDALDQLKSCRGRSCSIRRHQNHLEGGSSAPLLPINQVHRNNKRKHSPLAGAV
GNYAFVGPRLDMEALPPIKRRKLSKYNRLTGSQQSHMKRRPWKQTPLQQSPRFLRTHSVTPAQA

Options for BLAST

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Database Cross Reference

Ensembl Gene
UniGene Dm.13781
PDB
RefSeq NP_524987.1
Pfam PF00884
PF12548