MAPK (protein family or complex)

General Information (Source: NCBI Gene,UniProt)

Text mining Term MAPK (protein family or complex)
UniProt ID SUR8_DROSI
Name Protein Sur-8 homolog
Leucine-rich repeat protein soc-2 homolog
Protein soc-2 homolog
Gene Names
Taxonomy Drosophila simulans

General annotation

Function Acts as a Ras effector and participates in MAPK pathway activation. Probably acts as a regulatory subunit of protein phosphatase that specifically dephosphorylates Raf kinase and stimulate Raf activity at specialized signaling complexes upon Ras activation (By similarity).
Subcellular location

Sequence

>gi|261277896|sp|B4QVR7.2|SUR8_DROSI RecName: Full=Leucine-rich repeat protein soc-2 homolog; AltName: Full=Protein Sur-8 homolog; AltName: Full=Protein soc-2 homolog
MNLCSSGATASTTSLSSTGQAERSGGVPGGGAEGGGGGGGSGNSGGGGKTSDVSAEASTLCFAGGSGTAG
AITGTEELSNANSPANGAGGASGSTGSGQQPTGSNGHSHLHNENNANMPPETRPKMVTVKHPESNKPKPT
TKKSKPIQADQDVIKALQRCRIKRLDLSKSSITVIPSTVKECVHLTELYLYSNKIGQLPPEIGCLVSLRN
LALNENSLTSLPESLQNCSQLKVLDLRHNKLAEIPPVIYRLRSLTTLYLRFNRITAVADDLRQLVNLTML
SLRENKIRELGSAIGALVNLTTLDVSHNHLEHLPEDIGNCVNLSALDLQHNELLDIPDSIGNLKSLVRLG
MRYNRLSSVPATLKNCKSMDEFNVEGNGITQLPDGMLASLSGLTTITLSRNQFASYPTGGPAQFTNVYSI
NLEHNRIDKIPYGIFSRAKGLTKLNMKENMLTALPLDIGTWVNMVELNLATNALQKLPDDIMNLQNLEIL
ILSNNMLKKIPNTIGNLRRLRILDLEENRIEVLPHEIGLLHELQRLILQTNQITMLPRSIGHLGNLTHLS
VSENNLQFLPEEIGSLESLENLYINQNPGLEKLPFELALCQNLKYLNIDKCPLSTIPPEIQAGGPSLVLQ
WLKMHSPYRQIDCYYQYELQTVNQAPGAGGNGGGGAAAAGGSASRSSDRR

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Database Cross Reference

Ensembl Gene
UniGene Dsi.333
PDB
RefSeq XP_002103077.1
Pfam PF00560