chloride channel (protein family or complex)

General Information (Source: NCBI Gene,UniProt)

Text mining Term chloride channel (protein family or complex)
UniProt ID GBRB_LYMST
Name Gamma-aminobutyric acid receptor subunit beta
GABA(A) receptor
Gene Names
Taxonomy Lymnaea stagnalis

General annotation

Function GABA, an inhibitory neurotransmitter, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
Subcellular location Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.

Gene Ontology

GO:0034707 chloride channel complex CC
GO:0030054 cell junction CC
GO:0005886 plasma membrane CC
GO:0004890 GABA-A receptor activity MF
GO:0005254 chloride channel activity MF
GO:0045211 postsynaptic membrane CC
GO:0005230 extracellular ligand-gated ion channel activity MF

Sequence

>gi|120781|sp|P26714.1|GBRB_LYMST RecName: Full=Gamma-aminobutyric acid receptor subunit beta; AltName: Full=GABA(A) receptor; Flags: Precursor
MWGIIVPFFSASLMCSLVAVVRCQQDTDHFANVTNTIDSLLKGYDIRLRPSFGGAPLEIGIEVILASFDS
ISEVDMDYTITMYLNQYWRDERLQFIFNESLDLGENRSVTTMTLTGAFAEKIWVPDTFLANDKNSFLHDI
TEKNKMVRLYGNGSLVYGMRFTTTLACMMDLHNYPLDHQECTVEIESYGYTMDDIVLYWLNDRGAVTGVE
DVSLPQFSITNYATINKIEELSTGDYQRLSLIFQLQRNIGYFIFQTYLPSILIVMLSWVSFWINHEATSA
RVALGITTVLTMTTISNGVRSSLPRISYVKAIDIYLVMCFVFVFAALLEYAAVNYTYWGARAKRKAKRLR
ERATSVRKRVDDGDQMNNTNMDTVELKEVHMVPTSVGVTNSQSFNLDLDDGSGDDTGFRVVPPIPRSFTH
SHATTHGYIPTNVVRRRSSSHVPPRRRRLLSHFRQKAKSIKVKIPRVQDVNTIDKYARLMFPLLFIIFNT
SYWSVYLLT

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Database Cross Reference

Ensembl Gene
UniGene
PDB
RefSeq
Pfam PF02932
PF02931