sodium channel (protein family or complex)

General Information (Source: NCBI Gene,UniProt)

Text mining Term sodium channel (protein family or complex)
UniProt ID SCN1_LOLBL
Name Sodium channel protein I brain
Sodium channel protein 1 brain
Gene Names
Taxonomy Loligo bleekeri

General annotation

Function Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
Subcellular location Membrane; Multi-pass membrane protein.

Gene Ontology

GO:0001518 voltage-gated sodium channel complex CC
GO:0005248 voltage-gated sodium channel activity MF

Sequence

>gi|287449|dbj|BAA03398.1| sodium channel [Loligo bleekeri]
MDEKYTAKNRDKTFVVIEKRFKKNIIHRFSAKRSLFLFTPRNPIRRLAVCIATNVCFDYFLMFTIMINCV
FLAMPDISEFAEYIFLGIYTMEMAIKLVAGGFFIDKYTYLRDAWNCLDFTVIMISYITLLLQTINDKVIS
DITGLRTFRVLRALRTLSIIPGLKTMVNALLRALRMLISVLILILFCLWIFSQAGVQLFGGALRHKCVLQ
IHGSPAFGKTYDEFYAEHIENSDNWLAKGNGEYVLCGNATGAGPCPTNYTCLPDIGENPNYGYTNFDSIG
WSMLISFQLLTQDYWEDVYNKVIRAHSPWTVIYFIVINFFGSLYLMNLMLAVVATAYELEVKNTGKKLQQ
TAATAREQSLKEQERRNTLTVSEADSHVDDRNCTCCEQCCGCCYNPWLRVQSFAHCIITDSFTEVFIIFI
IVLNTVFLAMEHHGMSMELKNVLKVANYVFTTVFVLEAILKLLAFNKQYFKSGWNICDLVVVVASLIDLG
VEGLKGVSVFRSFRLLRVFHLAQSWTTMRLLLCIILNTLGSLGYLTIILIIVIYIFAVTGLQLFHTEYTP
DKFRGEPVPRWNFNDFLHSFMMVFRILCGEWIEPMYDCMRACNGLCFLIFIPVTVFGKTLFFLFIGLVLG
AFGSDTVEQEVEVSSFALPGPESKPCSVRERGISATDDNVKDDGQDEVQQNSEETKIDLRNNDKQSKDGM
ILENNCNNDSLASLGSLGSIPDIMDGSSVEDDISSCQQKDIQPCLPLFISSRFKCLREFDDTSHGKKWNN
FRRQLMMVCENKYFETGVLVIIFASSILLAFEDIYLNEKPRLKLAIFYLDITFCLLFFLEMVLKLVALGF
VHYYTHFWTILDFTIVIITVISLAASGLGMEQITAFRSLRTLRALRPLRAVSRWQGMKIIVNALMLSIPS
IFNVLLVCVVFWLIFAIMGVQLFAGKFYKCVNETNMRIPPTEVANKIECYNKNYTWVNSNVNFDNVGGAF
LALFQVATFEGWMEIMADAVDVTEVDEQPKFEATVYYYFYFVLFIIFGSFFVLNLVIGVIIDKFSFLKKK
YDGTYLDMFLTPTQQNYYNTLKKLGTKKPQKTVKRPKNKCQAVVYDLVMSNQFEIFITTIIITNMIFMAF
EHYNQSEVVTEVLATANIAFTILYAVEAIIKIIGLRIHYLRNLWNVFDFLVVTLSVMDAFLNDIFGDGIF
MNPSLLRVARMFRIGRIIRLIKWAKGMRKLLFALVISLPALFNIGALLMLVMFIYTIIGMSSFGQIKLSG
ALNDQVNFQTFGKTFLLLVRLATSAGWNDILGPLLIQPPNCDPNYITTSTGEKIKVVNGDCGMPWLAISY
MVSYIIIVFMIVFNMYIAVILENFNQAHAQEEVGITEDDLDMFYGVWEQYDPLATQFIKHEQLSDFIQDL
DPPLKVKKPNNVAIATFDLPIVKGGHIHCLDILLALVKFALGGNLEETEAFKRVRTQMEARFDEIFPTRE
KSEIRTSTLQMRREEMAARTLQRAWKRRKIMRSFPSPEMIRYFIISAPETAV

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Database Cross Reference

Ensembl Gene
UniGene
PDB
RefSeq
Pfam PF06512
PF00520