elongation factor 2

General Information (Source: NCBI Gene,UniProt)

Text mining Term	elongation factor 2
UniProt ID	EF2_PICGU
Name	Elongation factor 2 EF-2
Gene Names	EFT2
Taxonomy	Meyerozyma guilliermondii ATCC 6260

General annotation

Function	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity).
Subcellular location	Cytoplasm (By similarity).

Function

Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity).

Subcellular location

Cytoplasm (By similarity).

Gene Ontology

GO:0003924	GTPase activity	MF
GO:0005737	cytoplasm	CC
GO:0005525	GTP binding	MF
GO:0003746	translation elongation factor activity	MF

Sequence

>gi|146418435|ref|XP_001485183.1| elongation factor 2 [Meyerozyma guilliermondii ATCC 6260]
MVAFTIEQIRDLMDKVANVRNMSVIAHVDHGKSTLTDSLVQRAGIISAGKAGEARFMDTRKDEQERGITI
KSTAISLYASMDDDDVKEIKQKTDGNSFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDTVEGVCVQTE
TVLRQALGERIKPVLVVNKVDRALLELQVSKEDLYQTFARTVESVNVIISTYVDPALGDAQVYPDKGTVA
FGSGLHGWAFTVRQFALRYSKKFGVDRAKMMERLWGDSFFNPKTKKWTNKDKDADGKPLERAFNMFVLDP
IFRLFAAIMNFKKDEIPTLLEKLEINLKNEEKELEGKALLKVVMRKFLPAADALLEMIVLHLPSPVTAQA
YRAETLYEGPSDDEFCTAIRNCDPKADLMLYVSKMVPTSDKGRFYAFGRVFAGTVKAGQKIRIQGPNYTP
GKKEDLFLKSIQRTVLMMGRNTEAIDDCPAGNIVGLVGVDQFLLKSGTITTNEAAHNMKVMKFSVSPVVE
VAVEVKNANDLPKLVEGLKRLSKSDPCVKTYMSESGEHIVAGTGELHLEICLSDLQNDHAGIPLRISDPV
VAYRETIQAESSMVALSKSPNKHNRIYVKAQPIDEEVSLDIENGIINPRDDFKARARILADKHGWDVAEA
RKIWCFGPDGNGPNLVVDQTKAVQYLNEIKDSVVAAFQWATKEGPIFGENVRSVRVNILDVTLHADAIHR
GGGQIIPTMRRVTYASMLLAEPAIQEPVFLVEIQCPENAIGGIYSVLNKKRGQVVSEEQRPGTPLFTVKA
YLPVNESFGFSGDLRQATGGQAFPQLVFDHWAVLSGDVTDPTSKPGIIAKAKRERQGLKPEVPGYEEYYD
KL

Database Cross Reference

Ensembl Gene
UniGene
PDB
RefSeq	XP_001485183.1
Pfam	PF03144 PF00009 PF00679 PF03764

PTID

elongation factor 2

General Information (Source: NCBI Gene,UniProt)

General annotation

Gene Ontology

Sequence

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Database Cross Reference