ATPases

General Information (Source: NCBI Gene,UniProt)

Text mining Term ATPases
UniProt ID ATP6_RHOPD
Name ATP synthase subunit a
F-ATPase protein 6
Gene Names
Taxonomy Rhopalosiphum padi

General annotation

Function Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane (By similarity).
Subcellular location Mitochondrion inner membrane; Multi-pass membrane protein.

Gene Ontology

GO:0015078 hydrogen ion transmembrane transporter activity MF
GO:0016021 integral to membrane CC
GO:0015986 ATP synthesis coupled proton transport BP
GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o) CC
GO:0005743 mitochondrial inner membrane CC

Sequence

>gi|27805421|sp|Q9B6H6.1|ATP6_RHOPD RecName: Full=ATP synthase subunit a; AltName: Full=F-ATPase protein 6
MTTNLFNIFDPSTTIFNLEMNWISTLLIILFMPNFLWILPNRMNWLLFKMFNMLNNEMLMLYKMKKTKSP
AFLFISLFMFILLNNFFSLFPYIFSSSSHMVFSVTLAIPFWMFFIILSTCKNTKNMIAHLIPLNTPIYLA
PLMTIIETMSIIIRPMSLSIRLTANLIAGHLLMTLLNFNSLMIIIIFIQMFMMIFELCVALIQSYVFSIL
SSLYSSE

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Database Cross Reference

Ensembl Gene
UniGene
PDB
RefSeq
Pfam PF00119