ATPase

General Information (Source: NCBI Gene,UniProt)

Text mining Term ATPase
UniProt ID VATH_MANSE
Name V-ATPase subunit H
V-type proton ATPase subunit H
Vacuolar proton pump subunit H
Gene Names
Taxonomy Manduca sexta

General annotation

Function Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates the ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system (By similarity).
Subcellular location

Gene Ontology

GO:0015991 ATP hydrolysis coupled proton transport BP
GO:0005488 binding MF
GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain CC
GO:0046961 proton-transporting ATPase activity, rotational mechanism MF

Sequence

>gi|12585497|sp|Q9U5N0.1|VATH_MANSE RecName: Full=V-type proton ATPase subunit H; Short=V-ATPase subunit H; AltName: Full=Vacuolar proton pump subunit H
MANIGDEKVSQLIPTLGDDKIDMIAATSVLQIRASEIRQTQINWQSYLQGQMITQRDHDFIVNLDQRGQK
DLPDKNPDACADVFLNLLTHISKDHTIQYILVLIDDILSEDKSRVKIFRETKYSGNIWQPFLNLLNRQDE
FVQHMTARIIAKLACWHPQLMDKSDLHFYLSWLKDQLKMNNNDYIQSVARCLQMMLRVDEYRFAFLSVDG
ISTLLSILASRVNFQVQYQLVFCLWVLTFNPLLAEKMNKFNAIPILADILSDSVKEKVTRIVLAVFRNLI
EKPQDQQVAKEHCIAMVQCKVLKQLSILEQKRSDDEDIMNDVEFLNERLQASVQDLSSFDQYATEVKSGR
LEWSPVHKSAKFWRENAARLNERGQELLRTLVHLLEKSHDPVVLAVACYDVGEYVRHYPRGKHIIEQLGG
KQRVMYLLSHDDPNVRYEALLAVQKLMVHNWEYLGKQLEKEQIDKQAGTVVGAKA

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Database Cross Reference

Ensembl Gene
UniGene
PDB
RefSeq
Pfam PF11698
PF03224