C32

General Information (Source: NCBI Gene,UniProt)

Text mining Term C32
UniProt ID THIO2_DROME
Name DmTrx-2
Thioredoxin-2
Gene Names
Taxonomy Drosophila melanogaster

General annotation

Function Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. As a reducing substrate of peroxiredoxin 1, thioredoxin 2 is preferred over thioredoxin 1.
Subcellular location

Gene Ontology

GO:0006662 glycerol ether metabolic process BP
GO:0009055 electron carrier activity MF
GO:0008340 determination of adult lifespan BP
GO:0015035 protein disulfide oxidoreductase activity MF
GO:0045454 cell redox homeostasis BP
GO:0006810 transport BP
GO:0022900 electron transport chain BP
GO:0006974 response to DNA damage stimulus BP
GO:0006979 response to oxidative stress BP
GO:0005634 nucleus CC

Sequence

>gi|56967273|pdb|1XW9|D Chain D, Drospohila Thioredoxin, Oxidized, P21
MVYQVKDKADLDGQLTKASGKLVVLDFFATWCGPCKMISPKLVELSTQFADNVVVLKVDVDECEDIAMEY
NISSMPTFVFLKNGVKVEEFAGANAKRLEDVIKANI

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Database Cross Reference

Ensembl Gene
UniGene Dm.2664
PDB 1XW9
1XWA
1XWC
1XWB
RefSeq NP_723475.1
NP_523526.1
Pfam PF00085