CF 1 (protein family or complex)

General Information (Source: NCBI Gene,UniProt)

Text mining Term CF 1 (protein family or complex)
UniProt ID ATP4_PEA
Name F-ATPase delta' subunit
ATP synthase subunit delta', mitochondrial
Gene Names
Taxonomy Pisum sativum

General annotation

Function Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP turnover in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element. Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.
Subcellular location Mitochondrion. Mitochondrion inner membrane.

Gene Ontology

GO:0046961 proton-transporting ATPase activity, rotational mechanism MF
GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1) CC
GO:0005743 mitochondrial inner membrane CC
GO:0046933 hydrogen ion transporting ATP synthase activity, rotational mechanism MF
GO:0015986 ATP synthesis coupled proton transport BP

Sequence

>gi|2493047|sp|Q41000.1|ATP4_PEA RecName: Full=ATP synthase subunit delta', mitochondrial; AltName: Full=F-ATPase delta' subunit; Flags: Precursor
MFRRATSTFLSRASATRRFSTDVATPATNSSFVEAWRKVSPNIDPPKTPLEFLKTRPPVPSTIPTKLTVN
FVLPYSSQLAAKEVDSVIIPATTGEMGVLPGHVATIAELKPGVLTVQEGTDTTKYFVSSGFRFIHANSVA
DIIAVEAVPVNQLDRDLVQKGLQEFTQKLNSATTDLEKREAQIGIDVDSALNSALTG

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Database Cross Reference

Ensembl Gene
UniGene
PDB
RefSeq
Pfam PF02823