proliferating cell nuclear antigen

General Information (Source: NCBI Gene,UniProt)

Text mining Term proliferating cell nuclear antigen
UniProt ID C5FFQ0_ARTOC
Name Proliferating cell nuclear antigen
Gene Names
Taxonomy Arthroderma otae CBS 113480

General annotation

Function This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand (By similarity).
Subcellular location Nucleus (By similarity).

Gene Ontology

GO:0003677 DNA binding MF
GO:0005634 nucleus CC
GO:0043626 PCNA complex CC
GO:0006260 DNA replication BP
GO:0006275 regulation of DNA replication BP
GO:0030337 DNA polymerase processivity factor activity MF

Sequence

>gi|296818267|ref|XP_002849470.1| proliferating cell nuclear antigen [Arthroderma otae CBS 113480]
MPRYTSKLPASEAFLGGQGEAEQEWMPQEVDWPQTECSDSTTVDFAPQGPPKFQDRIRNKIPEPLKLKRP
NRPEALARIHDTCAGVVKAAISARIGKTDNERFREQFGYTIIASQLLSEPSAPSYTSVSNLLSHPPQSDE
DRATSRAAVFGVRVAAFYIFAKRQWLRYLRCQAIETATACVGNAQTLDSAASASVVLIQEELTTSTNGGE
ADIARWSAASEEMHSLADASAEWIEKLRDILNEQDRDIIAPSPMANLNPNPNKDRYRAQLRRLNSLSQGI
RGLHARMQLIREESDACLDRPGEDVDLSSTLLAQYEAIGAELRGILQEWEAGKSSMRANMETSDRYSSSS
RRTSSMIKSPSSPTFSIGGSTAVDGGPADALRALNGEMEKSTNPDSNMDDEEVFEAIAMPRTRSSMTRVE
RIARMKEDRARQAAMDNSHVALVSMMLKAEGFSPFRCDRNVALGINLVSLTKVLRAAQDGDVLTLKADDT
PDVVNLLFESVEKDRVSEYDIKLMDIDQEHLAIPETDYSATVEMPSAEFRRICGDLNQLSESVLIEASKD
GVRFSCQGEIGNGAVTIRQNTNVDKPEQNVSITLTESVALTFSIKYLLNFCKATSLSSKVRLSLSAEVPL
LVEYTLDGSGYVRFYLAPKIGEDE

Options for BLAST

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Database Cross Reference

Ensembl Gene
UniGene
PDB
RefSeq XP_002849470.1
Pfam PF02747
PF00705