proliferating cell nuclear antigen

General Information (Source: NCBI Gene,UniProt)

Text mining Term proliferating cell nuclear antigen
UniProt ID A5E400_LODEL
Name Proliferating cell nuclear antigen
Gene Names
Taxonomy Lodderomyces elongisporus NRRL YB-4239

General annotation

Function This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand (By similarity).
Subcellular location Nucleus (By similarity).

Gene Ontology

GO:0006260 DNA replication BP
GO:0006275 regulation of DNA replication BP
GO:0030337 DNA polymerase processivity factor activity MF
GO:0003677 DNA binding MF
GO:0005634 nucleus CC
GO:0043626 PCNA complex CC

Sequence

>gi|149236980|ref|XP_001524367.1| proliferating cell nuclear antigen [Lodderomyces elongisporus NRRL YB-4239]
MLEGKFDESTFLKKIVDAIKDSVKLCNFNCTEHGITVQAVDDSRVLLVSLLVGQTAFSEYRCDRDVTLGI
DLESFSKIIKCGQNEDYLTLLADENPDSVMTIFEDKKRERVSEYNLKLMNIDSEFLKIDDMDYDSVINMP
SAEFSKIVRDLKNLSESLNIIVTKDSVKFTSEGETGSGSVVLKPYTDIEKPDESVSVHLDNPVDLTFGLK
YLNDIVKGASLSSSITIKLADKTPALFEFKLAVGGYLRFYLAPKFDEDE

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Database Cross Reference

Ensembl Gene
UniGene
PDB
RefSeq XP_001524367.1
Pfam PF02747
PF00705