zinc finger protein

General Information (Source: NCBI Gene,UniProt)

Text mining Term zinc finger protein
UniProt ID ZFS1_SCHPO
Name Zinc finger protein zfs1
Multicopy suppressor of overexpressed cyr1 protein 4
Gene Names zfs1
Synonyms:moc4
Taxonomy Schizosaccharomyces pombe 972h-

General annotation

Function Binds to specific AU-rich elements (ARE) in the 3'- untranslated region of target mRNAs and promotes their degradation. Binds to ARE present in the arz1 mRNA and stimulates the rate of arz1 mRNA decay. Required for coordination of septum formation with exit from mitosis. Involved in the mating response pathway. Induces sexual development and ascus formation.
Subcellular location Cytoplasm. Nucleus.

Gene Ontology

GO:0031030 negative regulation of septation initiation signaling cascade BP
GO:0005829 cytosol CC
GO:0007049 cell cycle BP
GO:0035925 mRNA 3'-UTR AU-rich region binding MF
GO:0008270 zinc ion binding MF
GO:0007094 mitotic cell cycle spindle assembly checkpoint BP
GO:0031137 regulation of conjugation with cellular fusion BP
GO:0000750 pheromone-dependent signal transduction involved in conjugation with cellular fusion BP
GO:0005515 protein binding MF
GO:0005634 nucleus CC
GO:0006402 mRNA catabolic process BP
GO:0051301 cell division BP

Sequence

>gi|19113245|ref|NP_596453.1| zinc finger protein [Schizosaccharomyces pombe 972h-]
MVYSPMSRPQVPLAFRQWPPYNYKSDPLVNSKLSQSTTSVNAGPSLISPSFLDSYANSSSLLHKPSTNLG
SLKTSSLLASDEVFPSSVMPQLRPLDSSLSVSPEMDGWPWHHNSSSNPQGYAWTPSLLSSNATSYLHSGS
SPHGNTSNHPSPISSLESLPSRSSTGSGSLDFSGLANLHDDSKSLAMSLNMAGVPVSVDENSQTSFPFVH
GQPESTMSRKPKLCVQSKSMTNIRNSVAKPSLVRQSHSAGVIPIKPTASNASIRNAPSNLSKQFSPSGNS
PLTEASKPFVPQPSAAGDFRQAKGSASHPHGSGSSNGVAPNGKRALYKTEPCKNWQISGTCRYGSKCQFA
HGNQELKEPPRHPKYKSERCRSFMMYGYCPYGLRCCFLHDESNAQKSATIKQSP

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Database Cross Reference

Ensembl Gene
UniGene
PDB
RefSeq NP_596453.1
Pfam PF00642