Cytochrome c oxidase (protein family or complex)

General Information (Source: NCBI Gene,UniProt)

Text mining Term Cytochrome c oxidase (protein family or complex)
UniProt ID F8WSE2_9HEMI
Name Cytochrome c oxidase subunit 1
Gene Names coi
Taxonomy Trigonotylus caelestialium

General annotation

Function Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B (By similarity).
Subcellular location Mitochondrion inner membrane; Multi-pass membrane protein (By similarity).

Gene Ontology

GO:0009055 electron carrier activity MF
GO:0005739 mitochondrion CC
GO:0016021 integral to membrane CC
GO:0004129 cytochrome-c oxidase activity MF
GO:0020037 heme binding MF
GO:0009060 aerobic respiration BP

Sequence

>gi|340007149|dbj|BAK52538.1| cytochrome c oxidase subunit I [Trigonotylus caelestialium]
MFGMWSGMLGSSLSWIIRIELGMPGSFIGDDQTYNVVVTAHAFIMIFFMVMPIMIGGFGNWLVPLMIGAP
DMAFPRMNNMSFWLLPPALTLLTMSSIVENGAGTGWTVYPPLSSNLSHNGASVDLAIFSLHLAGVSSILG
AVNFISTIINMRPNGMHLEQIPLFVWSVGITALLLLLSLPVLAGAITMLLTDRNFNTSFFDPSGGGDPIL
YQHLFWFFGHPEVYILILPGFGLISHMISQESGKNETFGCLGMIYAMMAIGLLGFIVWAHHMFTVGMDVD
TRAYFTSATMIIAVPTGIKIFSWLATMHGTNINYSAPMLWSMGFVFLFTMGGLTGVILANSSIDIVLHDT
YYVVAHFHYVLSMGAVFAIIGSFIQWYPLFT

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Database Cross Reference

Ensembl Gene
UniGene
PDB
RefSeq
Pfam PF00115