metalloproteinase

General Information (Source: NCBI Gene,UniProt)

Text mining Term metalloproteinase
UniProt ID NPIIB_AJEDS
Name Neutral protease 2 homolog BDBG_02110
Deuterolysin BDBG_02110
Gene Names
Taxonomy Ajellomyces dermatitidis SLH14081

General annotation

Function Secreted metalloproteinase that allows assimilation of proteinaceous substrates. Shows high activities on basic nuclear substrates such as histone and protamine (By similarity).
Subcellular location Secreted (By similarity).

Gene Ontology

GO:0005576 extracellular region CC
GO:0006508 proteolysis BP
GO:0004222 metalloendopeptidase activity MF
GO:0046872 metal ion binding MF

Sequence

>gi|261205404|ref|XP_002627439.1| metalloproteinase [Ajellomyces dermatitidis SLH14081]
MQLSSVLLTAAGLLAPVYSSAIISIGRRSEGLDVSLASTGNTKVQVSVTNTGSSEISILRANTLFDASPT
KKFTVYKEGSRKEVPFKGVHLRRSPSDLAKDNLQPIGPGQTIDKEFDLAETLNLSESGTYIVSADGVFPI
IDPKSFSIASVIPYESNELKIEVDGKQVSGVLSTRAKIHDHLAQRADFNNGNCTDHQKAVIASALKRDSS
IAGEASNAALSGDVRVFEQYFRTTDPSIRQQVSDRFHAISNEACSAEGGVVKYQCEDEMDVCRPGTVAYA
LLGSNVVVNCPIYYSVTAVSQACDAGDQALTVIHELSHIDAVYYPATTDLAYGEDASMALNADMSIRNAD
SYTFYANAVRQNCNPS

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Database Cross Reference

Ensembl Gene
UniGene
PDB
RefSeq XP_002627439.1
Pfam PF02102