metalloproteinase

General Information (Source: NCBI Gene,UniProt)

Text mining Term metalloproteinase
UniProt ID NPIIC_ARTGP
Name Neutral protease 2 homolog MGYG_02351
Deuterolysin MGYG_02351
Gene Names
Taxonomy Arthroderma gypseum CBS 118893

General annotation

Function Secreted metalloproteinase that allows assimilation of proteinaceous substrates. Shows high activities on basic nuclear substrates such as histone and protamine. May be involved in virulence (By similarity).
Subcellular location Secreted (By similarity).

Gene Ontology

GO:0006508 proteolysis BP
GO:0009405 pathogenesis BP
GO:0004222 metalloendopeptidase activity MF
GO:0005576 extracellular region CC
GO:0046872 metal ion binding MF

Sequence

>gi|315050894|ref|XP_003174821.1| metalloproteinase [Arthroderma gypseum CBS 118893]
MQFVALLAALGAPLALAASIPAAHNNSSIIDVKLAATGNSMIKAIITNNGDRTLNLLKFNTIMDEHPTRK
VKVYQDGAEVQFTGMLPRYKMSDLTPDFFVNLGPKASVEHSFDLAATHDLSRGGKITVSANGVVPTAEEN
ETTITGHTHYESNELTMDVDGKEAAAVEQSMGGDSPAGVIDKRSNIVTSSCRGNQLQMLKTALANSARLS
KAAASAAQRNPRKFQEYFKTTDSSTVQKVVSRFMSVARESTSTGKTTYYCNDTRDGCKPGVLAYTLPSKN
QVFNCPSYYKLPALNNRCHGQDMATTTLHELTHNPAVVTPFCEDLGYGYDRVSRLPASKAVQNADTYSLF
ANAVYLGC

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Database Cross Reference

Ensembl Gene
UniGene
PDB
RefSeq XP_003174821.1
Pfam PF02102