calcium channel (protein family or complex)

General Information (Source: NCBI Gene,UniProt)

Text mining Term calcium channel (protein family or complex)
UniProt ID TPC1_WHEAT
Name Two pore calcium channel protein 1
TaTPC1
Voltage-dependent calcium channel protein TPC1
Gene Names TPC1
Taxonomy Triticum aestivum

General annotation

Function Functions as a voltage-gated inward-rectifying Ca(2+) channel (VDCC) across the plasma membrane that mediates sucrose- induced Ca(2+) influx in autotrophically grown leaf cells. Acts as the major ROS-responsive Ca(2+) channel and is the possible target of Al-dependent inhibition. Plays a regulatory role in defense responses.
Subcellular location Membrane; Multi-pass membrane protein.

Gene Ontology

GO:0005509 calcium ion binding MF
GO:0005262 calcium channel activity MF
GO:0006952 defense response BP
GO:0005244 voltage-gated ion channel activity MF
GO:0016021 integral to membrane CC

Sequence

>gi|75325199|sp|Q6YLX9.1|TPC1_WHEAT RecName: Full=Two pore calcium channel protein 1; AltName: Full=Voltage-dependent calcium channel protein TPC1; Short=TaTPC1
MSEAEAPLITEEAAERGLASSGSRRLSDGAGGQGSRKYRRRSDALAYGDRYQKAAALVDLAEDGVGIPED
VLNDTRFGRAMSFYFVYLRLDWLWSLNLFALILLNFLEKPLWCRKDALQAYDQRDLYFLGQLPYFSKTES
LIYEGLTLVILVMDIFCPLSYEGLNIFWRSTTNKLKIVLLFILACDILVFAFSSQPFRLAPYIRVVFLIM
TIRELRMCAITLAGLIGTYLNVLALSLLFLLFASWLAYVTFEDTPQGKTIFSSYGVTLYQMFVLFTTSNN
PDVWVHAYKIPRWYSLFFIVYVLLGVYFLTNLILAVIYDSFKEQFAKQLVQVDSIRKNILQKAFDLIDTN
NRGYLDREQCISLLNELNKYRSLPKTSREDFELIFAELDRSGDFKVTSEEFADLCNTIAIKFQKEPPPSY
LEKFPFYHSPLCGRLKSFVRSRMFEYIIVFVLLINLVAVIIETTLDIENSSSQETWQEVEFFLGWIYVAE
MALKIFSLGFGAYWMEGQNKFDFVLTWTIFIGETLTFAFPSKLPFLSNGEWIRYLLLGRVLRLTRILLQV
QRFRAFVATFFTLMSSLMPYLGIVFCVLCMYCSIGLQIFGGIVYAGNPTLEETDLFNNDYLLFNFNDYPS
GMVTLFNLLVMGNWQVWMESYWQLTGTSWSLIYFVSFYLISILLLLNLIVAFVLEAFFAEMELEKGEEVD
IQNPTSGGIKKRRSMRVRSKGTMVDILLHHMLSNELDGSQNS

Options for BLAST

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Database Cross Reference

Ensembl Gene
UniGene Ta.46666
PDB
RefSeq
Pfam PF00520