CELL

General Information (Source: NCBI Gene,UniProt)

Text mining Term CELL
UniProt ID TBA1_ELEIN
Name Tubulin alpha-1 chain
Alpha-1-tubulin
Gene Names TUBA1
Synonyms:TUA1
Taxonomy Eleusine indica

General annotation

Function Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.
Subcellular location Cytoplasm, cytoskeleton.

Gene Ontology

GO:0005525 GTP binding MF
GO:0007018 microtubule-based movement BP
GO:0003924 GTPase activity MF
GO:0005198 structural molecule activity MF
GO:0005737 cytoplasm CC
GO:0005874 microtubule CC
GO:0051258 protein polymerization BP

Sequence

>gi|6094429|sp|O22347.1|TBA1_ELEIN RecName: Full=Tubulin alpha-1 chain; AltName: Full=Alpha-1-tubulin
MRECISIHIGQAGIQVGNACWELYCLEHGIQADGQMPGDKTIGGGDDAFNTFFSETGAGKHVPRAVFVDL
EPTVIDEVRTGTYRQLFHPEQLISGKEDAANNFARGHYTIGKEIVDLCLDRIRKLADNCTGLQGFLVFNA
VGGGTGSGLGSLLLERLSVDYGKKSKLGFTVYPSPQVSTSVVEPYNSVLSTHSLLEHTDVAVLLDNEAIY
DICRRSLDIERPTYTNLNRLVSQVISSLTASLRFDGALNVDVNEFQTNLVPYPRIHFMLSSYAPVISAEK
AYHEQLSVAEITNSAFEPSSMMAKCDPRHGKYMACCLMYRGDVVPKDVNAAVATIKTKRTIQFVDWCPTG
FKCGINYQPPSVVPGGDLAKVQRAVCMISNSTSVVEVFSRIDHKFDLMYAKRAFVHWYVGEGMEEGEFSE
AREDLAALEKDYEEVGAEFDEGEEGDEGDEY

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Database Cross Reference

Ensembl Gene
UniGene
PDB
RefSeq
Pfam PF03953
PF00091