Protein Information

Name gamma glutamyl transferase
Synonyms CD224; CD224 antigen; D22S672; D22S732; GGT; GGT 1; GGT1; GGT1 protein…

Compound Information

Name chlorpyrifos
CAS

Reference List

PubMed Abstract RScore(About this table)
9323231 Vodela JK, Dalvi RR: Effect of chlorpyrifos on hepatic gamma-glutamyl transferase, serum cholinesterase and xenobiotic metabolizing enzyme activities in rats. Bull Environ Contam Toxicol. 1997 Nov;59(5):796-801.
31(0,1,1,1) Details
10025366 Gomes J, Dawodu AH, Lloyd O, Revitt DM, Anilal SV: Hepatic injury and disturbed amino acid metabolism in mice following prolonged exposure to organophosphorus pesticides. Hum Exp Toxicol. 1999 Jan;18(1):33-7.

Laboratory mice were exposed to a formulated mixture of the six organophosphorus pesticides (Dimethoate, Chlorpyrifos, Profenofos, Pirimiphos methyl, Triazophos and Dimethoate) most commonly used in agriculture in this region of the Middle East.
There were also non-significant increases in serum alkaline phosphatase, gama-glutamyl transpeptidase and some of the other amino acids.
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7535964 Vodela JK, Dalvi RR: Comparative toxicological studies of chlorpyrifos in rats and chickens. Vet Hum Toxicol. 1995 Feb;37(1):1-3.

Serum gamma-glutamyl transferase, a marker of hepatotoxicity, remained unchanged in both species, indicating the absence of hepatotoxicity.
1(0,0,0,1) Details