Name | demethylase |
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Synonyms | DMTase; Demethylase; MBD 2; MBD2; Methyl CpG binding domain protein 2; Methyl CpG binding protein MBD2; NY CO 41; Demethylases… |
Name | chlorpyrifos |
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CAS |
PubMed | Abstract | RScore(About this table) | |
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7722883 | Lodovici M, Aiolli S, Monserrat C, Dolara P, Medica A, Di Simplicio P: Effect of a mixture of 15 commonly used pesticides on DNA levels of metabolizing enzymes in rat liver. J Environ Pathol Toxicol Oncol. 1994;13(3):163-8. The level of 8-OH- in rat liver DNA was measured as an index of oxidative damage after treating rats for 10 days at a dose ranging from 0.75 to 10 mg/kg with a mixture of 15 pesticides (dithiocarbamate, benomyl, thiabendazole, diphenylamine, chlorthalonil, procimidone, methidathion, chlorpyrifos-ethyl, fenarimol, parathion-methyl, chlorpropham, parathion, vinclozolin, chlorfenvinphos, pirimiphos-ethyl) commonly found in foods of central Italy. The administration of the pesticide mixture dose dependently reduced benzo (a) pyrene hydroxylase, N-demethylase activities, peroxidase, glutathione reductase, glutathione-S-transferase and thiol transferase activities in the liver. |
and xenobiotic 1(0,0,0,1) | Details |
7535964 | Vodela JK, Dalvi RR: Comparative toxicological studies of chlorpyrifos in rats and chickens. Vet Hum Toxicol. 1995 Feb;37(1):1-3. Oral administration resulted in decreased cytochrome P-450 and aminopyrine N-demethylase activities and increased cytosolic glutathione S-transferase activity in rats. |
2(0,0,0,2) | Details |
10661713 | Valles SM, Koehler PG, Brenner RJ: Comparative insecticide susceptibility and detoxification enzyme activities among pestiferous blattodea. Comp Biochem Physiol C Pharmacol Toxicol Endocrinol. 1999 Nov;124(3):227-32. Lambda-Cyhalothrin LD50 correlated with methoxyresorufin O-demethylase activity (P = 0.01; r = 0.81), carboxylesterase activity (P = 0.03; r = - 0.75), general esterase activity (P = 0.02; r = - 0.79), and cockroach weight (P = 0.01; r = -0.95). Topical bioassays using propoxur, chlorpyrifos, and lambda-cyhalothrin were conducted on eight cockroach species. |
1(0,0,0,1) | Details |
11976062 | Valles SM, Woodson WD: Insecticide susceptibility and detoxication enzyme activities among Coptotermes formosanus Shiraki workers sampled from different locations in New Orleans. Comp Biochem Physiol C Toxicol Pharmacol. 2002 Apr;131(4):469-76. The termites were subsequently assayed to determine their susceptibility to cypermethrin, chlordane and chlorpyrifos, and detoxication enzyme activity. |
0(0,0,0,0) | Details |
1719272 | Pence BC, Demick DS, Richard BC, Buddingh F: The efficacy and safety of chlorpyrifos (Dursban) for control of Myobia musculi infestation in mice. Lab Anim Sci. 1991 Apr;41(2):139-42. |
0(0,0,0,0) | Details |