Protein Information

Name p38
Synonyms AIMP 2; p38; AIMP2; JTV 1; JTV1; JTV1 gene; JTV1 protein; Multisynthetase complex auxiliary component p38…

Compound Information

Name chlorpyrifos
CAS

Reference List

PubMed Abstract RScore(About this table)
14976342 Newhouse K, Hsuan SL, Chang SH, Cai B, Wang Y, Xia Z: Rotenone-induced apoptosis is mediated by p38 and JNK MAP kinases in human dopaminergic SH-SY5Y cells. Toxicol Sci. 2004 May;79(1):137-46. Epub 2004 Feb 19.

4(0,0,0,4) Details
14691213 Caughlan A, Newhouse K, Namgung U, Xia Z: Chlorpyrifos induces apoptosis in rat cortical neurons that is regulated by a balance between p38 and ERK/JNK MAP kinases. Toxicol Sci. 2004 Mar;78(1):125-34. Epub 2003 Dec 22.

Furthermore, chlorpyrifos activates the ERK1/2 and p38 MAP kinases.
250(3,3,4,5) Details
18155347 Saulsbury MD, Heyliger SO, Wang K, Round D: Characterization of chlorpyrifos-induced apoptosis in placental cells. Toxicology. 2008 Feb 28;244(2-3):98-110. Epub 2007 Oct 30.

In addition, our data further indicates that activation of p38 MAPK is integral to the protection cells against CPF-induced injury.
1(0,0,0,1) Details