| Name | P glycoprotein |
|---|---|
| Synonyms | ABC20; MDR1; ABCB 1; ABCB1; ATP binding cassette sub family B member 1; CD243; CD243 antigen; CLCS… |
| Name | chlorpyrifos |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 8600291 | Lanning CL, Fine RL, Sachs CW, Rao US, Corcoran JJ, Abou-Donia MB: Chlorpyrifos oxon interacts with the mammalian multidrug resistance protein, P-glycoprotein. J Toxicol Environ Health. 1996 Mar;47(4):395-407. |
421(5,5,7,11) | Details |
| 11744161 | Yang J, Mutkus LA, Sumner D, Stevens JT, Eldridge JC, Strandhoy JW, Aschner M: Transendothelial permeability of chlorpyrifos in RBE4 monolayers is modulated by astrocyte-conditioned medium. Brain Res Mol Brain Res. 2001 Dec 16;97(1):43-50. Additional studies were carried out to determine whether chlorpyrifos is a substrate for the multidrug resistance protein, P-glycoprotein (P-gp). |
81(1,1,1,1) | Details |
| 15130596 | Agarwala S, Chen W, Cook TJ: Effect of chlorpyrifos on efflux transporter gene expression and function in Caco-2 cells. Toxicol In Vitro. 2004 Aug;18(4):403-9. The effect of chlorpyrifos (CPF) and its metabolite, chlorpyrifos-oxon (CPO), on multidrug resistance-1 (MDR1) gene expression and efflux transporter function in Caco-2 cells was determined. |
32(0,1,1,2) | Details |
| 12109718 | Buss DS, McCaffery AR, Callaghan A: Evidence for p-glycoprotein modification of insecticide toxicity in mosquitoes of the Culex pipiens complex. Med Vet Entomol. 2002 Jun;16(2):218-22. increased toxicity to examples of three insecticide classes (cypermethrin, endosulfan, ivermectin), but not to chlorpyrifos (organophosphate). |
7(0,0,0,7) | Details |