Protein Information

Name phosphatidylinositol 3 kinase (protein family or complex)
Synonyms PI3 kinase; PI3 kinases; PI3K; Phosphatidylinositol 3 kinase; Phosphatidylinositol 3 kinases; Phosphatidylinositol 4,5 bisphosphate 3 kinase; Phosphatidylinositol 4,5 bisphosphate 3 kinases

Compound Information

Name chlorpyrifos
CAS

Reference List

PubMed Abstract RScore(About this table)
11083088 Bomser J, Casida JE: Activation of extracellular signal-regulated kinases (ERK 44/42) by chlorpyrifos oxon in Chinese hamster ovary cells. J Biochem Mol Toxicol. 2000;14(6):346-53.

ERK 44/42 activation by CPO is insensitive to the protein kinase A inhibitor H-89, but is completely abolished by the phosphatidylinositol 3-kinase (P13-K) inhibitor wortmannin, the protein kinase C (PKC) inhibitor GF-109203X, and the mitogen-activated extracellular signal-regulated protein kinase kinase (MEK) inhibitor PD 098059.		 1(0,0,0,1) Details