Protein Information

Name androgen receptor
Synonyms AIS; AR; Androgen receptor; DHTR; Dihydrotestosterone receptor; HUMARA; KD; NR3C4…

Compound Information

Name chlorpyrifos
CAS

Reference List

PubMed Abstract RScore(About this table)
11884232 Andersen HR, Vinggaard AM, Rasmussen TH, Gjermandsen IM, Bonefeld-Jorgensen EC: Effects of currently used pesticides in assays for estrogenicity, androgenicity, and aromatase activity in vitro. Toxicol Appl Pharmacol. 2002 Feb 15;179(1):1-12.

In addition, chlorpyrifos, deltamethrin, tolclofos-methyl, and tribenuron-methyl induced weak responses in one or both estrogenicity assays.
Twenty-four pesticides were tested for interactions with the estrogen receptor (ER) and the androgen receptor (AR) in transactivation assays.
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20211256 Viswanath G, Chatterjee S, Dabral S, Nanguneri SR, Divya G, Roy P: Anti-androgenic endocrine disrupting activities of chlorpyrifos and piperophos. J Steroid Biochem Mol Biol. 2010 Mar 6.

Various chemicals (mostly pesticides and pharmaceuticals) were screened with the NIH3T3 cell line stably expressing human androgen receptor (hAR) and luciferase reporter gene for their ability to stimulate luciferase activity or inhibit the response that was evoked by 0.4nM testosterone.
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