| PubMed |
Abstract |
RScore(About this table) |
| 17194553 |
Goel A, Dani V, Dhawan DK: Zinc mediates normalization of hepatic drug metabolizing enzymes in chlorpyrifos-induced toxicity. Toxicol Lett. 2007 Feb 28;169(1):26-33. Epub 2006 Dec 9.
The effects of different treatments were studied on the specific activities of various drug metabolizing enzymes including cytochrome P (450), cytochrome b (5), NADPH cytochrome-c-reductase, NADH cytochrome-c-reductase, aminopyrene-N-demethylase (APD) and aromatic hydrocarbon hydroxylase (AHH). |
1(0,0,0,1) |
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| 18447001 |
Cho TM, Rose RL, Hodgson E: The effect of chlorpyrifos-oxon and other xenobiotics on the human cytochrome P450-dependent metabolism of naphthalene and deet. Drug Metabol Drug Interact. 2007;22(4):235-62.
This metabolic activation is independent of cytochrome b5, suggesting that activation of CYP3A4 by CPO is associated with a conformational change of the isoform rather than facilitating electron transfer. |
1(0,0,0,1) |
Details |
| 15896444 |
Pope CN, Karanth S, Liu J, Yan B: Comparative carboxylesterase activities in infant and adult liver and their in vitro sensitivity to chlorpyrifos oxon. Regul Toxicol Pharmacol. 2005 Jun;42(1):64-9. Epub 2005 Feb 24.
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0(0,0,0,0) |
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