| Name | neurotoxic esterase |
|---|---|
| Synonyms | NTE; SWS; Neuropathy target esterase; Neurotoxic esterase; PNPLA 6; patatin like phospholipase domain containing 6; Neuropathy target esterases… |
| Name | fenitrothion |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 3775780 | Durham HD, Ecobichon DJ: An assessment of the potential of fenitrothion in the hen. Toxicology. 1986 Nov;41(3):319-32. Hens (2.0-2.5 kg body wt) received single oral doses of fenitrothion (500 mg/kg) or TOTP (500 mg/kg), the resulting toxicity being assessed by measuring biochemical (brain and spinal cord acetylcholinesterase (AChE) and neurotoxic esterase (NTE), physiological (motor function) and morphological (cross- and longitudinally-sectioned and stained preparations) parameters of the brains, spinal cords and sciatic nerves of groups (n = 5) of hens at 24 h, 7, 14, 28, 42 and 56 days post-treatment. |
31(0,1,1,1) | Details |
| 2453943 | Farage-Elawar M, Francis BM: Effects of fenthion, fenitrothion and desbromoleptophos on gait, acetylcholinesterase, and neurotoxic esterase in young chicks after in ovo exposure. Toxicology. 1988 May;49(2-3):253-61. |
7(0,0,1,2) | Details |
| 2449534 | Farage-Elawar M, Francis BM: Effects of multiple dosing of fenthion, fenitrothion, and desbromoleptophos in young chicks. J Toxicol Environ Health. 1988;23(2):217-28. The effects of multiple doses of desbromoleptophos, fenitrothion, and pure fenthion on brain acetylcholinesterase (AChE), brain neurotoxic esterase (NTE), and walking were investigated in immature chicks, below the age of sensitivity to organophosphorus ester-induced delayed neurotoxicity (OPIDN). |
6(0,0,1,1) | Details |
| 2439699 | Farage-Elawar M, Francis BM: Acute and delayed effects of fenthion in young chicks. J Toxicol Environ Health. 1987;21(4):455-69. The effects of desbromoleptophos, fenitrothion, and fenthion on brain acetylcholinesterase (AChE), brain neurotoxic esterase (NTE), and walking were investigated in immature chicks, below the age of organophosphorus ester-induced delayed neurotoxicity (OPIDN). |
6(0,0,1,1) | Details |
| 10321902 | Barber D, Correll L, Ehrich M: Comparative effectiveness of organophosphorus protoxicant activating systems in neuroblastoma cells and brain homogenates. J Toxicol Environ Health A. 1999 May 14;57(1):63-74. The ability of and rat liver microsomes (RLM) to convert organophosphorus (OP) protoxicants to esterase inhibitors was determined by measuring acetylcholinesterase (AChE) and neuropathy target esterase (NTE) inhibition. OP protoxicants examined included tri-o-tolyl (TOTP), O-ethyl O-p-nitrophenyl phenylphosphonothioate (EPN), leptophos, fenitrothion, fenthion, and malathion. |
1(0,0,0,1) | Details |
| 8511793 | Veronesi B, Ehrich M: Differential cytotoxic sensitivity in mouse and human cell lines exposed to organophosphate insecticides. Toxicol Appl Pharmacol. 1993 Jun;120(2):240-6. Baseline activities of the major target esterases, i.e., cholinesterase, carboxylesterase, and neurotoxic esterase, were assayed in mouse and several human neural candidate cell lines. IC50 data indicated that the tested mouse cell line was consistently more sensitive than the human cell line to equimolar doses of various OP compounds (e.g., mipafox, parathion, paraoxon, DFP, leptophos oxon, fenthion, and fenitrothion). |
1(0,0,0,1) | Details |