| Name | cytochrome P450 (protein family or complex) |
|---|---|
| Synonyms | cytochrome P450; cytochrome P 450; CYP450; CYP 450 |
| Name | fipronil |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 17427179 | Joo H, Choi K, Rose RL, Hodgson E: Inhibition of fipronil and nonane metabolism in human liver microsomes and human cytochrome P450 isoforms by chlorpyrifos. J Biochem Mol Toxicol. 2007;21(2):76-80. |
162(2,2,2,2) | Details |
| 15135087 | Tang J, Amin Usmani K, Hodgson E, Rose RL: In vitro metabolism of fipronil by human and rat cytochrome P450 and its interactions with and diazepam. Chem Biol Interact. 2004 Apr 15;147(3):319-29. |
37(0,1,2,2) | Details |
| 18977275 | Leghait J, Gayrard V, Picard-Hagen N, Camp M, Perdu E, Toutain PL, Viguie C: Fipronil-induced disruption of thyroid function in rats is mediated by increased total and free clearances concomitantly to increased activity of hepatic enzymes. Toxicology. 2009 Jan 8;255(1-2):38-44. Epub 2008 Oct 9. The same fipronil treatment increased antipyrine clearance in thyroid-intact rats suggesting an increase in the activity of cytochrome P450 enzymes. |
6(0,0,1,1) | Details |
| 9461846 | Bride JM, Cuany A, Amichot M, Brun A, Babault M, Mouel TL, De Sousa G, Rahmani R, Berge JB: Cytochrome P-450 field insecticide tolerance and development of laboratory resistance in grape vine populations of Drosophila melanogaster (Diptera: Drosophilidae). J Econ Entomol. 1997 Dec;90(6):1514-20. Few significant variations of ECOD activity were detected among the natural populations despite many insecticide treatments, but activities were significantly correlated with toxicological tolerance to 5 of the 15 insecticides (deltamethrin, fipronil, chlorpyriphos ethyl, DDT, and diazinon). |
2(0,0,0,2) | Details |
| 12192904 | Durham EW, Siegfried BD, Scharf ME: In vivo and in vitro metabolism of fipronil by larvae of the European corn borer Ostrinia nubilalis. Pest Manag Sci. 2002 Aug;58(8):799-804. Cytochrome P450-dependent monooxygenase activity (methoxyresorufin O-demethylase) was consistently observed in midgut preparations, and formation and detection of the sulfone metabolite in the same midgut preparations was also -dependent and inhibited by piperonyl butoxide. |
1(0,0,0,1) | Details |