Protein Information

Name protoporphyrinogen oxidase
Synonyms Mutant protoporphyrinogen oxidase; VP; PPO; PPOX; Protoporphyrinogen oxidase; V290M; Protoporphyrinogen oxidases

Compound Information

Name diuron
CAS

Reference List

PubMed Abstract RScore(About this table)
16506820 Aliferis KA, Chrysayi-Tokousbalides M: Metabonomic strategy for the investigation of the mode of action of the phytotoxin (5S,8R,13S,16R)-(-)-pyrenophorol using 1H nuclear magnetic resonance fingerprinting. J Agric Food Chem. 2006 Mar 8;54(5):1687-92.

Analysis results revealed that none of the herbicide treatments fitted the pyrenophorol model and indicate that the effect of the phytotoxin on A. sterilis differs than those caused by glyphosate, mesotrione, norflurazon, oxadiazon, paraquat, and diuron, which inhibit 5-enolpyruvylshikimate-3-phosphate synthase, 4-hydroxyphenyl-pyruvate-dioxygenase, phytoene desaturase, protoporphyrinogen oxidase, photosystem I, and photosystem II, respectively.
81(1,1,1,1) Details
2146157 Varsano R, Matringe M, Magnin N, Mornet R, Scalla R: Competitive interaction of three peroxidizing herbicides with the binding of [3H] acifluorfen to corn etioplast membranes. FEBS Lett. 1990 Oct 15;272(1-2):106-8.


The specific binding of the herbicide acifluorfen 5-[2-chloro-4-(trifluoromethyl) phenoxy]-2-nitrobenzoic acid to corn etioplast membranes is competitively inhibited by protoporphyrinogen IX, the substrate of protoporphyrinogen oxidase.
2(0,0,0,2) Details
16406601 Ma J, Wang S, Wang P, Ma L, Chen X, Xu R: Toxicity assessment of 40 herbicides to the green alga Raphidocelis subcapitata. Ecotoxicol Environ Saf. 2006 Mar;63(3):456-62.

The most toxic herbicides were atrazine, ametryme, simazine, prometryne, cyanazine, isoproturon, chlorotoluron, diuron, methabenzthiazuron, and paraquat.
The EC50 of the protoporphyrinogen oxidase inhibitor oxadiargyl, which was the parameter least sensitive to the herbicides tested in this study, was 42.5 mgL (-1).
2(0,0,0,2) Details