Protein Information

Name IL 12 (protein family or complex)
Synonyms Cytotoxic lymphocyte maturation factor; Cytotoxic lymphocyte maturation factors; IL 12; IL12; Natural killer cell stimulatory factor; Natural killer cell stimulatory factors

Compound Information

Name TCA
CAS 2,2,2-trichloroacetic acid

Reference List

PubMed Abstract RScore(About this table)
16237081 Lopez MV, Adris SK, Bravo AI, Chernajovsky Y, Podhajcer OL: IL-12 and IL-10 expression synergize to induce the immune-mediated eradication of established colon and mammary tumors and lung metastasis. J Immunol. 2005 Nov 1;175(9):5885-94.

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17464941 Chevallet M, Diemer H, Van Dorssealer A, Villiers C, Rabilloud T: Toward a better analysis of secreted proteins: the example of the myeloid cells secretome. Proteomics. 2007 Jun;7(11):1757-70.


These techniques have been used to analyze the secretome of myeloid cells (macrophages, dendritic cells) and enabled to analyze proteins secreted at concentrations close to 1 ng/mL, thereby allowing the detection of some of the cytokines (TNF, IL-12) secreted by the myeloid cells upon activation by bacterial products.
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