| Name | cytochrome P450 (protein family or complex) |
|---|---|
| Synonyms | cytochrome P450; cytochrome P 450; CYP450; CYP 450 |
| Name | TCA |
|---|---|
| CAS | 2,2,2-trichloroacetic acid |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19448409 | Jiang JG, Shen GF, Chen C, Fu XN, Wang DW: Effects of cytochrome P450 arachidonic acid epoxygenases on the proliferation of tumor cells. Ai Zheng. 2009 Jan;28(1):14-9. Epub 2009 Jan 5. METHODS: The effects of recombinant adeno-associated virus (rAAV) mediated cytochrome P450 2J2 (CYP2J2), cytochrome P450 F87V (CYPF87V) and anti-CYP2J2 on proliferation of Tca-8113, A549, Ncl-H446 and HepG2 cells were measured using MTT and flow cytometry. |
37(0,1,2,2) | Details |
| 17256530 | Marco-Urrea E, Gabarrell X, Sarra M, Caminal G, Vicent T, Reddy CA: Novel aerobic perchloroethylene degradation by the white-rot fungus Trametes versicolor. Environ Sci Technol. 2006 Dec 15;40(24):7796-802. Our studies using 1 -aminobenzotriazole (ABT), an inhibitor of cytochrome P-450, suggested that a cytochrome P-450 system may be involved in PCE degradation by T. versicolor. |
1(0,0,0,1) | Details |
| 15881660 | Selvendiran K, Thirunavukkarasu C, Singh JP, Padmavathi R, Sakthisekaran D: Chemopreventive effect of piperine on mitochondrial TCA cycle and phase-I and -metabolizing enzymes in benzo (a) pyrene induced lung carcinogenesis in Swiss albino mice. Mol Cell Biochem. 2005 Mar;271(1-2):101-6. Lung cancer bearing mice showed a significant decrease in the activities of mitochondrial enzymes-isocitrate dehydrogenase (ICDH), -ketoglutarate dehydrogenase (KDH), succinate dehydrogenase (SDH), malate dehydrogenase (MDH) and significantly increased -Cytochorome reductase -C reductase), cytochrome P450 (cyt-p450) and cytochrome b5 (cyt-b5). |
1(0,0,0,1) | Details |
| 16553509 | Kurpius MP, Alexander B: Rates of in vivo methylation of desipramine and nortriptyline. . Pharmacotherapy. 2006 Apr;26(4):505-10. Possible explanations for methylation include genetic polymorphisms in cytochrome P450 metabolizing enzymes, polymorphism of amine N-methyltransferase enzyme, drug-drug interactions, smoking, and consumption. |
1(0,0,0,1) | Details |
| 16921551 | Dragan CA, Blank LM, Bureik M: Increased TCA cycle activity and reduced consumption during cytochrome P450-dependent biotransformation in fission yeast. Yeast. 2006 Aug;23(11):779-94. |
1(0,0,0,1) | Details |
| 17471183 | Gillman PK: Tricyclic antidepressant pharmacology and therapeutic drug interactions updated. Br J Pharmacol. 2007 Jul;151(6):737-48. Epub 2007 Apr 30. New data on the pharmacology of tricyclic antidepressants (TCAs), their affinities for human cloned CNS receptors and their cytochrome P450 enzyme inhibition profiles, allow improved deductions concerning their effects and interactions and indicate which of the TCAs are the most useful. |
1(0,0,0,1) | Details |
| 18783381 | Campoy S, Alvarez-Rodriguez ML, Recio E, Rumbero A, Coque JJ: Biodegradation of 2,4,6-TCA by the white-rot fungus Phlebia radiata is initiated by a phase I (O-demethylation)-phase II (O-conjugation) reactions system: implications for the cycle. Environ Microbiol. 2009 Jan;11(1):99-110. Epub 2008 Sep 8. Phase I reaction consisted on a O-demethylation catalysed by a microsomal cytochrome P-450 monooxygenase to produce 2,4,6-trichlorophenol (2,4,6-TCP). |
1(0,0,0,1) | Details |