| Name | P glycoprotein |
|---|---|
| Synonyms | ABC20; MDR1; ABCB 1; ABCB1; ATP binding cassette sub family B member 1; CD243; CD243 antigen; CLCS… |
| Name | TCA |
|---|---|
| CAS | 2,2,2-trichloroacetic acid |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 15457126 | Di Nicolantonio F, Knight LA, Glaysher S, Whitehouse PA, Mercer SJ, Sharma S, Mills L, Prin A, Johnson P, Charlton PA, Norris D, Cree IA: Ex vivo reversal of chemoresistance by tariquidar (XR9576). Anticancer Drugs. 2004 Oct;15(9):861-9. The expression of P-glycoprotein (P-gp) has been demonstrated to confer resistance to several anticancer drugs, including anthracyclines, taxanes and vinca alkaloids. |
6(0,0,0,6) | Details |
| 17537309 | Gao GL, Wan HY, Zou XS, Chen WX, Chen YQ, Huang XZ: [Relationship between the expression of P-glycoprotein, glutathione S-transferase-pi and thymidylate synthase proteins and tumor chemosensitivity assay in cervical cancer]. Zhonghua Fu Chan Ke Za Zhi. 2007 Mar;42(3):201-5. |
3(0,0,0,3) | Details |
| 15457125 | Di Nicolantonio F, Knight LA, Di Palma S, Sharma S, Whitehouse PA, Mercer SJ, Charlton PA, Norris D, Cree IA: Ex vivo characterization of XR11576 (MLN576) against ovarian cancer and other solid tumors. Anticancer Drugs. 2004 Oct;15(9):849-60. Immunohistochemical staining of Topo I, Topo IIalpha and MDR1 was performed on paraffin-embedded blocks in those tumors for which tissue was available (n = 49). |
1(0,0,0,1) | Details |
| 12967592 | Elamiri A, Perwaiz S, Tuchweber B, Yousef IM: Effect of mdr2 mutation with combined tandem disruption of canalicular glycoprotein transporters by cyclosporine A on bile formation in mice. Pharmacol Res. 2003 Nov;48(5):467-72. The aim of this study is to evaluate the effects of various P-glycoprotein (Pgp) transporters on bile formation and the canalicular transport of (TCA) in an attempt to understand the combined role of these transporters in the pathogenesis of familial intrahepatic cholestasis. |
1(0,0,0,1) | Details |
| 16200870 | Zhou CZ, Li Y, Xu J: [Correlation between p53 gene mutation and the expression of tumor drug resistance genes in lung cancer and its clinical significance]. Zhonghua Jie He He Hu Xi Za Zhi. 2004 Oct;27(10):678-82. Immunohistochemical staining was employed for detection of both mutant p53 and drug-resistance associated proteins (MDR1, MRP1, LRP, TOPO II alpha, GST-pi), PCR-SSCP and RT-PCR were used for detection of mutations of p53 exon 5-8 as well as the expression of mRNAs for the genes coding those drug-resistance associated proteins in 31/66 cases. |
1(0,0,0,1) | Details |