Protein Information

Name cathepsin D
Synonyms CATD; CLN10; CPSD; CTSD; Cathepsin D; Cathepsin D precursor; cathepsin D (lysosomal aspartyl peptidase); cathepsin D (lysosomal aspartyl protease)…

Compound Information

Name TCA
CAS 2,2,2-trichloroacetic acid

Reference List

PubMed Abstract RScore(About this table)
19688284 Abdel-Hamid NM: Premalignant variations in extracellular matrix composition in chemically induced hepatocellular carcinoma in rats. J Membr Biol. 2009 Aug;230(3):155-62. Epub 2009 Aug 18.


This study explored premalignant changes in the liver tissue content of collagen (as hydroxyproline, HP), total glycosaminoglycans (TGAGs), free glucosamine (FGA), total sialic acid (TSA), lysosomal membrane integrity variations (calculated as total and free cathepsin D activities), and liver histology.
3(0,0,0,3) Details
20177669 Abdel-Hamid NM, Morsy MA: Novel biochemical pathways for 5-Fluorouracil in managing experimental hepatocellular carcinoma in rats. J Membr Biol. 2010 Mar;234(1):29-34. Epub 2010 Feb 23.


We executed both biochemical-serum alpha-fetoprotein (AFP), liver tissue contents of total glycosaminoglycan (TGAGs), collagen (represented as hydroxyproline), total sialic acid (TSA), free glucosamine (FGA) and proteolytic enzyme activity (as pepsin and free cathepsin-D-and histological examinations of the liver tissue.
1(0,0,0,1) Details