Protein Information

Name isocitrate dehydrogenase 1
Synonyms Cytosolic NADP isocitrate dehydrogenase; IDH; IDH 1; IDH1; IDH1 protein; IDP; Isocitrate dehydrogenase 1; Isocitrate dehydrogenase [NADP] cytoplasmic…

Compound Information

Name TCA
CAS 2,2,2-trichloroacetic acid

Reference List

PubMed Abstract RScore(About this table)
16232608 Asano T, Kurose N, Hiraoka N, Kawakita S: Effect of NAD+-dependent isocitrate dehydrogenase gene (IDH1, IDH2) disruption of sake yeast on organic acid composition in sake mash. J Biosci Bioeng. 1999;88(3):258-63.

2(0,0,0,2) Details
14568142 Wang ZX, Bramer C, Steinbuchel A: Two phenotypically compensating isocitrate dehydrogenases in Ralstonia eutropha. FEMS Microbiol Lett. 2003 Oct 10;227(1):9-16.


Two IDH genes icd1 and icd2 of Ralstonia eutropha HF39, encoding isocitrate dehydrogenase 1 (IDH1) and isocitrate dehydrogenase 2 (IDH2), were identified and characterized.
2(0,0,0,2) Details
20304625 Bayley JP, Devilee P: Warburg tumours and the mechanisms of mitochondrial tumour suppressor genes. Curr Opin Genet Dev. 2010 Mar 19.


Another mitochondrial and TCA cycle-related protein, isocitrate dehydrogenase 2 is, together with IDH1, frequently mutated in the brain tumour glioblastoma.
1(0,0,0,1) Details