| Name | GABA transaminase |
|---|---|
| Synonyms | (S) 3 amino 2 methylpropionate transaminase; 4 aminobutyrate aminotransferase; ABAT; ABAT protein; GABA aminotransferase; GABA transaminase; GABA AT; GABA T… |
| Name | TCA |
|---|---|
| CAS | 2,2,2-trichloroacetic acid |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 16249254 | Wang C, Kerckhofs K, Van de Casteele M, Smolders I, Pipeleers D, Ling Z: inhibits release by pancreatic beta-cells through an increase in shunt activity. Am J Physiol Endocrinol Metab. 2006 Mar;290(3):E494-9. Epub 2005 Oct 25. Net production is the result of formation through decarboxylase (GAD) and catabolism involving a -transferase (GABA-T)-mediated shunt to the TCA cycle. |
6(0,0,0,6) | Details |
| 19513197 | Takahashi H, Matsumura H, Kawai-Yamada M, Uchimiya H: The cell death factor, cell wall elicitor of rice blast fungus (Magnaporthe grisea) causes metabolic alterations including shunt in rice cultured cells. Plant Signal Behav. 2008 Nov;3(11):945-53. is metabolized through a bypass pathway of the TCA cycle called shunt, which is composed of decarboxylase (GAD), GABA transaminase (GABA-T) and succinic semialdehyde dehydrogenase (SSADH). |
4(0,0,0,4) | Details |
| 18846220 | Ludewig F, Huser A, Fromm H, Beauclair L, Bouche N: Mutants of GABA transaminase (POP2) suppress the severe phenotype of succinic semialdehyde dehydrogenase (ssadh) mutants in Arabidopsis. PLoS One. 2008;3(10):e3383. Epub 2008 Oct 10. |
3(0,0,0,3) | Details |
| 17579816 | Madsen KK, Larsson OM, Schousboe A: Regulation of excitation by neurotransmission: focus on metabolism and transport. Results Probl Cell Differ. 2008;44:201-21. The inactivation of is brought about by high affinity transporters located in the presynaptic GABAergic neurons as well as surrounding astrocytes and subsequently may be metabolized by GABA-transaminase (GABA-T) ultimately allowing the carbon skeleton to enter the tricarboxylic acid (TCA) cycle for oxidative metabolism. |
2(0,0,0,2) | Details |
| 19576596 | Seo JY, Lee CH, Cho JH, Choi JH, Yoo KY, Kim DW, Park OK, Li H, Choi SY, Hwang IK, Won MH: Neuroprotection of ebselen against ischemia/reperfusion injury involves shunt enzymes. J Neurol Sci. 2009 Oct 15;285(1-2):88-94. Epub 2009 Jul 2. In this study, we observed the neuroprotective effects of ebselen against ischemic damage and on shunt enzymes such as glutamic acid decarboxylase 67 (GAD67), transaminse (GABA-T) and succinic semialdehyde dehydrogenase (SSADH) in the hippocampal CA1 region after 5 min of transient forebrain ischemia in gerbils. |
2(0,0,0,2) | Details |
| 16797191 | Yang J, Shen J: Increased oxygen consumption in the somatosensory cortex of alpha-chloralose anesthetized rats during forepaw stimulation determined using MRS at 11.7 Tesla. Neuroimage. 2006 Sep;32(3):1317-25. Epub 2006 Jun 21. With markedly improved (1) H{(13) C} magnetic resonance spectroscopy technique and the use of high magnetic field strength of 11.7 T accessible to the current study, [4-(13) C] at 2.35 ppm was spectrally resolved from overlapping resonances of [4-(13) C] at 2.46 ppm and [2-(13) C] GABA at 2.28 ppm as well as the more distal [3-(13) C] and [3-(13) C] |
1(0,0,0,1) | Details |
| 18035723 | Vinitskaia AG, Lelevich SV, Lelevich VV, Kozlovskii AV, Doroshenko EM: metabolism and neuroactive amino acids in the rat brain in morphine withdrawal syndrome]. Biomed Khim. 2007 Jul-Aug;53(4):427-34. In cerebellum MW led to the decrease in the levels of and and increase in level, followed by the GABA-transaminase activation and the succinate dehydrogenase inhibition. |
1(0,0,0,1) | Details |