Protein Information

Name Bcl xL
Synonyms Apoptosis regulator Bcl X; BCL XL/S; BCL2 like 1; BCL2 related gene; BCL2 like 1 isoform 1; BCL2L; BCL2L1; BCLX…

Compound Information

Name azobenzene
CAS diphenyldiazene

Reference List

PubMed Abstract RScore(About this table)
19012295 Kneissl S, Loveridge EJ, Williams C, Crump MP, Allemann RK: Photocontrollable peptide-based switches target the anti-apoptotic protein Bcl-xL. Chembiochem. 2008 Dec 15;9(18):3046-54.

Photocontrol of Bcl-x (L) binding affinity has been achieved by using short BH3 domain peptides for Bak (72-87) and Bid (91-111) alkylated with an azobenzene crosslinker through two cysteine residues with different sequence spacings.
36(0,1,1,6) Details