Protein Information

Name catalase
Synonyms CAT; Catalase; Erythrocyte derived growth promoting factor; Carnitine O acetyltransferase; Carnitine acetylase; Carnitine acetyltransferase; CAT; Catalases…

Compound Information

Name pyrethrins
CAS pyrethrins

Reference List

PubMed Abstract RScore(About this table)
11931506 Yarsan E, Bilgili A, Kanbur M, Celik S: Effects of deltamethrin on lipid peroxidation in mice. Vet Hum Toxicol. 2002 Apr;44(2):73-5.


Lipid peroxidation was evaluated by determining malondialdehyde (MDA) levels in plasma, and determining glutathione peroxidase (GSH-Px), superoxide dismutase (Cu-Zn SOD) and catalase activities in erythrocytes on days 15, 45, and 60.
2(0,0,0,2) Details
15892188 Prasanthi K, Muralidhara, Rajini PS: Morphological and biochemical perturbations in rat erythrocytes following in vitro exposure to Fenvalerate and its metabolite. Toxicol In Vitro. 2005 Jun;19(4):449-56.


At higher concentrations, significant decreases in the activities of vital antioxidant enzymes viz., catalase, superoxide dismutase, glutathione transferase and glutathione reductase were also discernible clearly suggesting the potency of both, parent compound and its metabolite to induce oxidative stress in erythrocytes.
1(0,0,0,1) Details
15266958 Jayasree U, Reddy AG, Reddy KS, Anjaneyulu Y, Kalakumar B: Evaluation of vitamin E against deltamethrin toxicity in broiler chicks. Indian J Physiol Pharmacol. 2003 Oct;47(4):447-52.


Weekly body weights, feed conversion ratio, glutathione (GSH) concentration and high density lipoproteins (HDL) were significantly (P < 0.05) reduced, while the activities of glutathione peroxidase (GSH-Px), glutathione reductase (GSH-R), catalase, aspartate aminotransferase (AST) and lactate dehydrogenase (LDH), and the lipid profile and renal biomarkers were increased significantly (P < 0.05) in group 2 and 3 at the end of 4th wk as compared to group 1.
1(0,0,0,1) Details
18214882 Kanbur M, Liman BC, Eraslan G, Altinordulu S: Effects of cypermethrin, propetamphos, and combination involving cypermethrin and propetamphos on lipid peroxidation in mice. Environ Toxicol. 2008 Aug;23(4):473-9.


Serum nitric oxide (NO) and plasma malondialdehyde (MDA) levels and erythrocyte superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px) activities were measured.
1(0,0,0,1) Details
15365239 Manna S, Bhattacharyya D, Mandal TK, Das S: Repeated dose toxicity of alfa-cypermethrin in rats. J Vet Sci. 2004 Sep;5(3):241-5.


It increased malondialdehyde (MDA) level, while decreased the activities of catalase (CAT), superoxide dismutase (SOD) and glycogen level in liver significantly.
1(0,0,0,1) Details
18946182 Eraslan G, Kanbur M, Silici S, Altinordulu S, Karabacak M: Effecs of cypermethrin on some biochemical changes in rats: the protective role of propolis. Exp Anim. 2008 Oct;57(5):453-60.


Serum glucose, triglyceride, uric acid, cholesterol, aspartate aminotransferase (AST), alanine aminotransferase (ALT) and alkaline phosphatase (ALP) activities/levels, plasma and tissue malondialdehyde (MDA) levels, and erythrocyte and tissue superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GSH-Px) activities were determined.
1(0,0,0,1) Details
19500828 Wang XZ, Liu SS, Sun Y, Wu JY, Zhou YL, Zhang JH: Beta-cypermethrin impairs reproductive function in male mice by inducing oxidative stress. Theriogenology. 2009 Sep 15;72(5):599-611. Epub 2009 Jun 4.


These toxic effects of beta-CYP may be mediated by increasing oxidative stress, as the moderate and high doses of this compound increased malondialdehyde and nitric oxide in testes (P <0.05); reduced the activity of catalase, glutathione peroxidase (GSH-Px), and superoxide dismutase (P <0.05); and activated ERK1/2 (P <0.05).
1(0,0,0,1) Details
12927561 Sayeed I, Parvez S, Pandey S, Bin-Hafeez B, Haque R, Raisuddin S: Oxidative stress biomarkers of exposure to deltamethrin in freshwater fish, Channa punctatus Bloch. Ecotoxicol Environ Saf. 2003 Oct;56(2):295-301.


Catalase activity was decreased in all the tissues.
1(0,0,0,1) Details
15114462 Shiyin L, Lixiao N, Panying P, Cheng S, Liansheng W: Effects of pesticides and their hydrolysates on catalase activity in soil. Bull Environ Contam Toxicol. 2004 Mar;72(3):600-6.

1(0,0,0,1) Details
16499895 Rehman H, Ali M, Atif F, Kaur M, Bhatia K, Raisuddin S: The modulatory effect of deltamethrin on antioxidants in mice. Clin Chim Acta. 2006 Jul 15;369(1):61-5. Epub 2006 Feb 24.


Along with the induction of LPO, activities of vital antioxidant enzymes such as glutathione peroxidase (GPx), glutathione S-transferase (GST) and catalase (CAT) were also suppressed in both the tissues.
1(0,0,0,1) Details
18587520 Koprucu SS, Yonar E, Seker E: Effects of deltamethrin on antioxidant status and oxidative stress biomarkers in freshwater mussel, Unio elongatulus eucirrus. Bull Environ Contam Toxicol. 2008 Sep;81(3):253-7. Epub 2008 Jun 28.


With increasing deltamethrin concentrations, the mussels exposed duration 1-96 h significantly increased lipid peroxidation, which might be associated to decreased levels of reduced glutathione and catalase activity in digestive gland and gill of freshwater mussel (p <0.05 for each cases).
1(0,0,0,1) Details
19067015 Liu J, Lu X, Xie J, Chu Y, Sun C, Wang Q: Adsorption of lambda-cyhalothrin and cypermethrin on two typical Chinese soils as affected by copper. Environ Sci Pollut Res Int. 2009 Jun;16(4):414-22. Epub 2008 Dec 6.


Our previous studies had indicated the combined effect of cypermethrin (CPM) and Cu on soil catalase activity.
1(0,0,0,1) Details
19687627 Raina R, Verma PK, Pankaj NK, Prawez S: Induction of oxidative stress and lipid peroxidation in rats chronically exposed to cypermethrin through dermal application. J Vet Sci. 2009 Sep;10(3):257-9.


Significant (p < 0.05) increase in catalase activity was observed after 30 days of exposure.
1(0,0,0,1) Details
16105448 Li HY, Shi N, Chen D, Dai ZH, Lu WH, Wang B, Li YR: [Oxidative stress of deltamethrin on rat nervous system] . Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2005 Apr;23(2):97-101.


The content of malondialdehyde (MDA) and the activity of total-superoxide dismutase (T-SOD, including Mn-SOD and CuZn-SOD), catalase (CAT), glutathione-S-transferase (GST), glutathione peroxidase (GSH-Px) and glutathione reductase (GR) in cerebral cortex and hippocampus tissue were determined.
1(0,0,0,1) Details
18665983 Harper HE, Pennington PL, Hoguet J, Fulton MH: Lethal and sublethal effects of the pyrethroid, bifenthrin, on grass shrimp (Palaemonetes pugio) and sheepshead minnow (Cyprinodon variegatus). J Environ Sci Health B. 2008 Aug;43(6):476-83.


Oxidative stress biomarkers, lipid peroxidation, glutathione, and catalase were also assessed.
1(0,0,0,1) Details
17055627 Bashir F, Mahmooduzzafar, Siddiqi TO, Iqbal M: The antioxidative response system in Glycine max (L.) Merr. exposed to Deltamethrin, a synthetic pyrethroid insecticide. Environ Pollut. 2007 May;147(1):94-100. Epub 2006 Oct 19.


Among the enzymatic antioxidants, activity of superoxide dismutase, ascorbate peroxidase and glutathione reductase increased significantly whereas that of catalase declined markedly in relation to increasing concentration of Deltamethrin applied.
1(0,0,0,1) Details
17137748 El-Demerdash FM: Lambda-cyhalothrin-induced changes in oxidative stress biomarkers in rabbit erythrocytes and alleviation effect of some antioxidants. Toxicol In Vitro. 2007 Apr;21(3):392-7. Epub 2006 Oct 1.


However, a significant decrease in the content of sulfhydryl groups (SH-groups), and the activities of acetylcholinesterase (AChE), superoxide dismutase (SOD), catalase (CAT) and glutathione S-transferase (GST) were observed.
1(0,0,0,1) Details
12965126 Nasuti C, Cantalamessa F, Falcioni G, Gabbianelli R: Different effects of Type I and Type II pyrethroids on erythrocyte plasma membrane properties and enzymatic activity in rats. Toxicology. 2003 Sep 30;191(2-3):233-44.


The different modifications induced by pyrethroids on lipid peroxidation, osmotic fragility and the antioxidant enzymes (superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx)) were measured.
1(0,0,0,1) Details
16842967 Sinha C, Seth K, Islam F, Chaturvedi RK, Shukla S, Mathur N, Srivastava N, Agrawal AK: Behavioral and neurochemical effects induced by pyrethroid-based mosquito repellent exposure in rat offsprings during prenatal and early postnatal period. Neurotoxicol Teratol. 2006 Jul-Aug;28(4):472-81. Epub 2006 Jul 13.


We observed significant oxidative stress, where an increase in lipid peroxidation and a decrease in antioxidants, glutathione, superoxide dismutase and catalase in various brain areas (cerebellum, corpus striatum, frontal cortex and hippocampus) were evident at all the exposure schedules.
1(0,0,0,1) Details