| Name | ATPase |
|---|---|
| Synonyms | ATP7A; MK; ATPase; Cation transporting ATPase; ATP7A protein; ATPase Cu(2+) transporting alpha polypeptide; Copper pump 1; Copper transporting ATPase 1… |
| Name | chloroform |
|---|---|
| CAS | trichloromethane |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 18296714 | Yamamoto K, Moomey M, Rajagopalan M, Madiraju MV: Facilitation of dissociation reaction of nucleotides bound to Mycobacterium tuberculosis DnaA. J Biochem. 2008 Jun;143(6):759-64. Epub 2008 Feb 22. Estimation of phospholipid following chloroform: extraction of soluble DnaA (TB) purified under native conditions (nDnaA (TB)) confirmed the association with phospholipids. nDnaA (TB) exhibited weak ATPase activity, and rapidly exchanged ATP for bound ADP in the absence of any added phospholipids. |
31(0,1,1,1) | Details |
| 18644203 | Freitas CS, Baggio CH, Finau J, Anginoni M, Pizzolatti MG, Santos AR, Marques MC: Inhibition of H+/K+ ATPase in the gastroprotective effect of Baccharis illinita DC. J Pharm Pharmacol. 2008 Aug;60(8):1105-10. The chloroform extract (CE) of flowers from B. illinita (3, 10, 30 and 100 mg kg (-1) i.p.) tested on rats with pylorus ligature reduced the volume and the total acidity of gastric content by approximately 50% (ED50 = 69 mg kg (-1)). |
4(0,0,0,4) | Details |
| 18498717 | Dos Santos AC, Baggio CH, Freitas CS, Lepieszynski J, Mayer B, Twardowschy A, Missau FC, dos Santos EP, Pizzolatti MG, Marques MC: Gastroprotective activity of the chloroform extract of the roots from Arctium lappa L. J Pharm Pharmacol. 2008 Jun;60(6):795-801. In-vitro, CE inhibited H+, K+ -ATPase activity with an EC50 of 53 microgmL (-1) and fraction A (30 and 100 microgmL (-1)) reduced this by 48% and 89%, respectively. |
2(0,0,0,2) | Details |
| 18758956 | Pereyra-Alfonso S, Del Valle Armanino M, Vazquez C, Pena C, Rodriguez de Lores Arnaiz G: High-affinity neurotensin receptor is involved in phosphoinositide turnover increase by inhibition of pump in neonatal rat brain. Neurochem Res. 2008 Nov;33(11):2206-13. Epub 2008 Aug 29. Peptide neurotensin inhibits synaptosomal membrane Na (+), K (+)-ATPase activity, an effect blocked by SR 48692, a selective antagonist for high-affinity neurotensin receptor (NTS1). Reaction was stopped with chloroform/ and [(3) H] inositol-phosphates (IPs) accumulation was quantified in the water phase. |
1(0,0,0,1) | Details |
| 19962286 | Lakshmi V, Singh N, Shrivastva S, Mishra SK, Dharmani P, Mishra V, Palit G: Gedunin and Photogedunin of Xylocarpus granatum show significant anti-secretory effects and protect the gastric mucosa of peptic ulcer in rats. Phytomedicine. 2009 Dec 2. Chloroform fraction (Fr-CHCl (3)) of X. granatum fruit was evaluated against cold restraint (CRU), (AS), (AL) and pyloric ligation (PL) induced gastric ulcer models in rats and (HA) induced duodenal ulcer model in guinea pigs. Further, Fr-CHCl (3) and its compounds gedunin and photogedunin significantly inhibited H (+) K (+)-ATPase activity in vitro with IC (50) of 89.37, 56.86 and 66.54mug/ml respectively as compared to the IC (50) value of (30.24mug/ml) confirming their anti-secretory activity. |
1(0,0,0,1) | Details |