| Name | cytochrome P450 (protein family or complex) |
|---|---|
| Synonyms | cytochrome P450; cytochrome P 450; CYP450; CYP 450 |
| Name | chloroform |
|---|---|
| CAS | trichloromethane |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 18031782 | Fang C, Behr M, Xie F, Lu S, Doret M, Luo H, Yang W, Aldous K, Ding X, Gu J: Mechanism of chloroform-induced renal toxicity: non-involvement of hepatic cytochrome P450-dependent metabolism. Toxicol Appl Pharmacol. 2008 Feb 15;227(1):48-55. Epub 2007 Oct 23. |
31(0,1,1,1) | Details |
| 20090406 | Neis MM, Wendel A, Wiederholt T, Marquardt Y, Joussen S, Baron JM, Merk HF: Expression and induction of cytochrome p450 isoenzymes in human skin equivalents. Skin Pharmacol Physiol. 2010;23(1):29-39. Epub 2010 Jan 14. RNA was isolated by -chloroform extraction and purified. |
2(0,0,0,2) | Details |
| 17479406 | Gu SY, Zhang ZB, Wan JX, Jin XP, Xia ZL: Genetic polymorphisms in CYP1A1, CYP2D6, UGT1A6, UGT1A7, and SULT1A1 genes and correlation with exposure in a Chinese occupational population. J Toxicol Environ Health A. 2007 Jun;70(11):916-24. Metabolic enzymes involved in activation or detoxification, including cytochrome P-450 1A1 (CYP1A1), cytochrome P-450 2D6 (CYP2D6), UDP-glucuronosyltransferase 1A6 (UGT1A6), UDP-glucuronosyltransferase1A7 (UGT1A7), and sulfotransferase 1A1 (SULT1A1), were studied for their roles in human susceptibility to poisoning. All 304 subjects were investigated with a unitary questionnaire and their DNA was isolated from blood samples by a routine -chloroform extraction. |
1(0,0,0,1) | Details |
| 18311635 | Chuman H: Toward basic understanding of the partition coefficient log P and its application in QSAR. SAR QSAR Environ Res. 2008 Jan-Mar;19(1-2):71-9. Next, an application of log P in QSAR analyses of ligand-CYP (Cytochrome P450) interaction was described. |
1(0,0,0,1) | Details |
| 18353473 | Van Aken B: Transgenic plants for phytoremediation: helping nature to clean up environmental pollution. Trends Biotechnol. 2008 May;26(5):225-7. Epub 2008 Mar 18. A recent publication by Doty and colleagues describes the development of transgenic poplars (Populus) overexpressing a mammalian cytochrome P450, a family of enzymes commonly involved in the metabolism of toxic compounds. The engineered plants showed enhanced performance with regards to the metabolism of trichloroethylene and the removal of a range of other toxic volatile organic pollutants, including vinyl carbon tetrachloride, chloroform and |
1(0,0,0,1) | Details |